{"id":"W4244165224","doi":"10.1002/1097-0215(20001101)88:3<401::aid-ijc12>3.3.co;2-m","title":"Induced neuroblastoma cell differentiation, associated with transient HES‐1 activity and reduced HASH1 expression, is inhibited by Notch1","year":2000,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Karolinska Institutet; Cancer Research Society","keywords":"Neuroblastoma; Transient (computer programming); Cellular differentiation; Cell; Cell biology; Biology; Expression (computer science); Endocrinology; Chemistry; Internal medicine; Cancer research; Medicine; Cell culture; Genetics; Gene; Computer science","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007597783,0.0001938679,0.0002230581,0.0001185922,0.0001335609,0.0001676671,0.0001476353,0.0001305972,0.001320443],"category_scores_gemma":[0.00006616064,0.0001037798,0.0001953878,0.0001213745,0.0001644187,0.00008674216,0.0002123775,0.0004293384,0.0003372679],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002561927,"about_ca_system_score_gemma":0.0003234161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001207754,"about_ca_topic_score_gemma":0.002849412,"domain_scores_codex":[0.9999049,0.000009083651,0.00001213559,0.00002166975,0.00003264675,0.00001950074],"domain_scores_gemma":[0.9999431,0.00001057704,0.0000126317,0.000008651585,0.000008125831,0.00001692041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005330486,0.00001551334,0.000188177,0.00002545533,0.000003208495,0.00003315834,0.00001277246,0.00002291608,0.9988413,0.00007594703,0.00003670434,0.0006914737],"study_design_scores_gemma":[0.000007437944,0.0001106229,0.00782246,0.000005375447,0.00000794263,0.0001327756,0.00001967476,0.000351761,0.9896154,0.00002354702,0.001900985,0.000002041695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924384,0.001682279,0.001835236,0.00005940197,0.00002986901,0.00003165649,0.000907306,0.00008793009,0.002928177],"genre_scores_gemma":[0.9887357,0.001434804,0.001305369,0.00004620897,0.000005057927,0.00006764501,0.001761626,0.00001814093,0.006625401],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001320443,"threshold_uncertainty_score":0.00441736,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006846837784142478,"score_gpt":0.2546723387061272,"score_spread":0.2478255009219847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}