{"id":"W4244265399","doi":"10.3410/f.1086932.793503067","title":"Faculty Opinions recommendation of The glucocorticoid agonist activities of mifepristone (RU486) and progesterone are dependent on glucocorticoid receptor levels but not on EC50 values.","year":2015,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Adrenal Hormones and Disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Mifepristone; Glucocorticoid; Glucocorticoid receptor; Agonist; Antiglucocorticoid; Progesterone receptor; EC50; Endocrinology; Chemistry; Internal medicine; Pharmacology; Receptor; Medicine; Biology; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00102232,0.0006250662,0.001482172,0.0002823656,0.0001809095,0.00007110797,0.0008782608,0.0006587699,0.0001573072],"category_scores_gemma":[0.00478651,0.0003539115,0.0005792429,0.0009732382,0.0006201089,0.0001941372,0.0004831973,0.00116678,0.00003254506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002238904,"about_ca_system_score_gemma":0.0008093342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006971612,"about_ca_topic_score_gemma":0.0000059457,"domain_scores_codex":[0.9945279,0.0004308659,0.001676724,0.0007585781,0.002244313,0.0003616328],"domain_scores_gemma":[0.9921049,0.0002122103,0.002552159,0.001801648,0.00304626,0.0002827453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002392424,0.001002736,0.00004552988,0.008976881,0.0002346047,3.70624e-7,0.0001608453,6.058962e-7,0.0000482036,0.00008938581,0.9862997,0.0029019],"study_design_scores_gemma":[0.00186963,0.0007752955,0.01153137,0.01608208,0.0004041439,0.00004533962,0.0002430035,0.000007737211,0.0005996978,0.00001325291,0.9681036,0.0003248088],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0003304649,0.001417613,0.000006718489,0.1222655,0.0007628847,0.003004457,0.8721318,0.00002224975,0.00005835008],"genre_scores_gemma":[0.001299763,0.0004681257,0.0001354588,0.004518593,0.0001492228,0.0002097339,0.9913224,0.00004108447,0.001855648],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.1191906,"threshold_uncertainty_score":0.9998913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04913343389731279,"score_gpt":0.3535222048405975,"score_spread":0.3043887709432848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}