{"id":"W4244579982","doi":"10.21203/rs.3.rs-17090/v1","title":"Antibodies from multiple sclerosis brain identified Epstein-Barr virus nuclear antigen 1 & 2 epitopes which are recognized by oligoclonal bands","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Anschutz Medical Campus, University of Colorado; National Institutes of Health; University of Glasgow","keywords":"Epitope; Antibody; Virology; Antigen; Multiple sclerosis; Phage display; Immunology; Virus; Biology; Immunoglobulin G; Molecular biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004011608,0.001486655,0.0004570852,0.001851602,0.000576331,0.0005827326,0.000529241,0.001022229,0.0123219],"category_scores_gemma":[0.0007927083,0.0003319979,0.000660102,0.0006030805,0.0003650232,0.0004828148,0.0006521742,0.001203762,0.00323996],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004253405,"about_ca_system_score_gemma":0.0002562335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008405076,"about_ca_topic_score_gemma":0.0007404213,"domain_scores_codex":[0.9997316,0.00002227518,0.0000258883,0.00006830103,0.0000531084,0.00009882462],"domain_scores_gemma":[0.9994062,0.0002359579,0.00006575877,0.0000696844,0.000120913,0.0001014643],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000505961,0.000150068,0.00122879,0.0003012927,0.00005984283,0.002271411,0.0002478586,0.00009700545,0.983898,0.001477402,0.000868713,0.00889369],"study_design_scores_gemma":[0.0003357137,0.001125789,0.06609523,0.0002483994,0.0003184918,0.02587539,0.0006540501,0.002141964,0.8514238,0.007090875,0.04462296,0.00006725873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9262567,0.007208862,0.01914193,0.0009546443,0.0007207432,0.0002473952,0.00181985,0.0003756822,0.04327419],"genre_scores_gemma":[0.9423414,0.005451882,0.01811607,0.0005597745,0.0007895888,0.0004419982,0.005169081,0.0001139921,0.02701624],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0123219,"threshold_uncertainty_score":0.0412209,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1665729966605977,"score_gpt":0.3881269486235387,"score_spread":0.221553951962941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}