{"id":"W4244644765","doi":"10.1111/j.1751-1097.2005.tb01542.x","title":"Calculation of Singlet Oxygen Dose from Photosensitizer Fluorescence and Photobleaching During mTHPC Photodynamic Therapy of MLL Cells<sup>¶</sup>","year":2005,"lang":"en","type":"article","venue":"Photochemistry and Photobiology","topic":"Photodynamic Therapy Research Studies","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juravinski Cancer Centre; McMaster University","funders":"","keywords":"Singlet oxygen; Photobleaching; Photosensitizer; Photodynamic therapy; Photochemistry; Chemistry; Fluorescence; Singlet state; Oxygen; Irradiation; Fluence; Viability assay; Biophysics; Cell; Optics; Organic chemistry; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003239683,0.0004250116,0.0009379524,0.0001366368,0.0001524269,0.00001373684,0.0001741504,0.0003134073,0.0001877165],"category_scores_gemma":[0.0001042146,0.0003794525,0.0001542047,0.0001906983,0.0007407716,0.00009699524,0.0001637713,0.0004702844,0.000002081697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008777639,"about_ca_system_score_gemma":0.00009467936,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009279272,"about_ca_topic_score_gemma":0.00002016073,"domain_scores_codex":[0.9977075,0.0001271742,0.0006888206,0.0007017251,0.000265182,0.0005095941],"domain_scores_gemma":[0.9984581,0.0003435507,0.0003076264,0.0005110589,0.0001658127,0.0002137872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002563824,0.0002535896,0.001750487,0.0002794892,0.0003295566,0.00002658785,0.002232167,0.00005017611,0.9905419,0.000001821011,0.0000256177,0.00194478],"study_design_scores_gemma":[0.004158807,0.0002789074,0.008975827,0.0002803701,0.00005719754,0.0001203179,0.0003628123,0.004655543,0.9803506,0.00007920394,0.0003762817,0.0003041043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955172,0.002745026,0.000007338755,0.00009122827,0.0000301582,0.001035269,0.0002517175,0.00005338961,0.0002686722],"genre_scores_gemma":[0.9943939,0.004107498,0.0009118489,0.0001155748,0.000114616,0.00007946895,0.0001215709,0.00004176186,0.0001137104],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01019127,"threshold_uncertainty_score":0.9998657,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01102286628729445,"score_gpt":0.2658423975587053,"score_spread":0.2548195312714108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}