{"id":"W4244794707","doi":"10.1007/978-3-319-48066-4_11","title":"Ipilimumab","year":2016,"lang":"en","type":"book-chapter","venue":"","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Ipilimumab; Medicine; CTLA-4; Melanoma; Monoclonal antibody; Adverse effect; Blockade; Oncology; Internal medicine; Clinical trial; Drug; Immune system; Metastatic melanoma; Receptor; Immunotherapy; Antibody; Cancer research; Pharmacology; Immunology; Cancer; T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001366295,0.0005771721,0.0002860839,0.0005175121,0.0002320846,0.0008732142,0.0003372893,0.0005125541,0.05034791],"category_scores_gemma":[0.0002377678,0.0001334058,0.0001715148,0.0004329993,0.0002077642,0.0008919074,0.0006091174,0.001609823,0.02793647],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000490217,"about_ca_system_score_gemma":0.0003327641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005073978,"about_ca_topic_score_gemma":0.001486052,"domain_scores_codex":[0.9999382,0.000009024659,0.000002457328,0.00001261927,0.00002866789,0.000008969137],"domain_scores_gemma":[0.9999677,0.00001123881,0.00000376232,0.000003256129,0.00000642836,0.000007602372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005528077,0.0000454994,0.00003777444,0.0002457829,0.000006359596,0.0001095279,0.0000338409,0.0002453368,0.00199617,0.01543179,0.2789611,0.7028314],"study_design_scores_gemma":[0.000007794387,0.00001278186,0.00006576311,0.0000854857,0.000003333451,0.0002492507,0.000005303209,0.00007329873,0.00043092,0.002856534,0.9962071,0.000002390453],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.001793349,0.1676862,0.007449848,0.008043668,0.006341477,0.00006121129,0.0004565685,0.0005627619,0.8076048],"genre_scores_gemma":[0.006898226,0.05623782,0.002392731,0.003689308,0.001509333,0.00005386033,0.0003639518,0.0001102282,0.9287445],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.05034791,"threshold_uncertainty_score":0,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02122487094835646,"score_gpt":0.259371798657386,"score_spread":0.2381469277090295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}