{"id":"W4245103331","doi":"10.1007/978-3-319-17169-2_59","title":"Alagille Syndrome","year":2015,"lang":"en","type":"book-chapter","venue":"","topic":"Pediatric Hepatobiliary Diseases and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; SickKids Foundation; University of Toronto","funders":"","keywords":"Alagille syndrome; Cholestasis; Notch signaling pathway; Liver disease; Natural history; Biology; Medicine; Genetics; Pathology; Internal medicine; Endocrinology; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001294248,0.0006547924,0.000304805,0.0006127771,0.000384575,0.0005917301,0.0003728038,0.0008962439,0.02510684],"category_scores_gemma":[0.0004472781,0.0001285918,0.0002596608,0.0003573971,0.0004262603,0.0007155768,0.0008169003,0.00175019,0.008286584],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005048405,"about_ca_system_score_gemma":0.0005300316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008343896,"about_ca_topic_score_gemma":0.001773824,"domain_scores_codex":[0.9999276,0.00001500268,0.000004433613,0.00001303248,0.00002813421,0.0000118215],"domain_scores_gemma":[0.9999441,0.0000235233,0.000004747976,0.000004614188,0.00001020784,0.00001274328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005001005,0.00007394208,0.0003279228,0.0002134341,0.00001563434,0.007401768,0.0002983564,0.0003879005,0.001732082,0.07925986,0.4684759,0.4417632],"study_design_scores_gemma":[0.00001070231,0.000019044,0.0002959899,0.000291333,0.000007365802,0.01363058,0.00004971155,0.00009007722,0.0002426532,0.01617231,0.9691815,0.000008669968],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"review","genre_scores_codex":[0.00402927,0.102281,0.007158639,0.0121565,0.007067611,0.00006673209,0.0002774316,0.0003376305,0.8666251],"genre_scores_gemma":[0.0259566,0.06922628,0.007439503,0.01345306,0.002828282,0.000113561,0.0004884168,0.0001532453,0.880341],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.02510684,"threshold_uncertainty_score":0.08399075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04329690947807654,"score_gpt":0.2779500958453754,"score_spread":0.2346531863672988,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}