{"id":"W4245477498","doi":"10.1007/978-1-4614-6438-9_382-1","title":"RSK (p90 Ribosomal S6 Kinase)","year":2016,"lang":"en","type":"book-chapter","venue":"","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Ribosomal s6 kinase; Chemistry; Biochemistry; P70-S6 Kinase 1; Phosphorylation; Protein kinase B","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001290556,0.0008853986,0.0003533733,0.000657679,0.0002239532,0.0009952214,0.0004854093,0.0004744236,0.02177498],"category_scores_gemma":[0.0001235263,0.0001998489,0.0002808692,0.0007389079,0.0002852581,0.001135832,0.0005514456,0.001231044,0.03640528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005615456,"about_ca_system_score_gemma":0.0003607403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005506205,"about_ca_topic_score_gemma":0.001219974,"domain_scores_codex":[0.999925,0.000003887871,0.000003511045,0.00002109194,0.00003847003,0.000008061696],"domain_scores_gemma":[0.9999766,0.000004927269,0.000003538168,0.000002984959,0.000007153351,0.000004767787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009368046,0.00005278589,0.00006187998,0.0006596944,0.00001028521,0.0001612829,0.00005115569,0.0006511158,0.04038552,0.02969923,0.1658691,0.7623043],"study_design_scores_gemma":[0.000003773455,0.00001659071,0.00009912661,0.00003469816,0.000003856888,0.0002520661,0.000006898925,0.00008750112,0.005829993,0.002909861,0.9907512,0.000004486091],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.005015885,0.2705525,0.02749884,0.003140538,0.006643828,0.00009411181,0.001558907,0.002017722,0.6834778],"genre_scores_gemma":[0.0133672,0.09642712,0.009641206,0.0007486331,0.0007927112,0.00006228357,0.001186722,0.0002327273,0.8775414],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.02177498,"threshold_uncertainty_score":0.07284456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01113592353144353,"score_gpt":0.2066748178172263,"score_spread":0.1955388942857828,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}