{"id":"W4245501240","doi":"10.1158/1538-7445.sabcs18-1449","title":"Abstract 1449: MG1 Maraba boost following adenovirus prime generates tumor antigen-specific T cells which are potentiated by anti-PD-1 antibody combination","year":2019,"lang":"en","type":"article","venue":"Immunology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Interface Biologics (Canada)","funders":"","keywords":"Antigen; Antibody; Prime (order theory); Cancer research; Molecular biology; Virology; Chemistry; Immunology; Medicine; Biology; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0005104956,0.0004085896,0.0008416858,0.0004283365,0.0001916074,0.0001177083,0.0004051748,0.0003725439,0.004816719],"category_scores_gemma":[0.00005788431,0.0004001737,0.000243903,0.0006932227,0.0001411164,0.0002496376,0.0001556587,0.0008569014,0.001956342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000237589,"about_ca_system_score_gemma":0.0001918308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002479198,"about_ca_topic_score_gemma":0.000008657525,"domain_scores_codex":[0.996931,0.0001951939,0.0006209929,0.0007746677,0.0005536818,0.0009244994],"domain_scores_gemma":[0.9981287,0.0001425015,0.0002876265,0.0008996854,0.0004096478,0.0001318994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004989284,0.0005610886,0.04372423,0.00004236123,0.0004928964,0.0002508545,0.00009662534,0.000005268802,0.9504348,0.00002461701,0.001987085,0.00188126],"study_design_scores_gemma":[0.004209679,0.0005350122,0.3316447,0.0001232055,0.0000297109,0.000101381,0.0002170727,0.00009979135,0.6368709,0.00001698176,0.02579732,0.0003542876],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9840662,0.009767023,0.00004239844,0.0007392736,0.00157709,0.001180735,0.00004807653,0.0001945307,0.002384714],"genre_scores_gemma":[0.9921525,0.002500474,0.00006893658,0.0001949282,0.000127968,0.00001950169,0.0007832336,0.0001191542,0.004033315],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3135639,"threshold_uncertainty_score":0.999845,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01415352416748518,"score_gpt":0.2842191339901131,"score_spread":0.270065609822628,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}