{"id":"W4245632703","doi":"10.1093/neuonc/noz175.054","title":"ACTR-11. SECOND INTERIM AND 1ST MOLECULAR ANALYSIS OF THE EORTC RANDOMIZED PHASE III INTERGROUP CATNON TRIAL ON CONCURRENT AND ADJUVANT TEMOZOLOMIDE IN ANAPLASTIC GLIOMA WITHOUT 1p/19q CODELETION","year":2019,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Temozolomide; Medicine; Internal medicine; Glioma; Interim analysis; Isocitrate dehydrogenase; Hazard ratio; Oncology; IDH1; Randomized controlled trial; Confidence interval; Radiation therapy; Cancer research; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006149733,0.001030697,0.001811357,0.0003643291,0.0003076906,0.001023229,0.0005420793,0.0009551416,0.005464816],"category_scores_gemma":[0.003137747,0.0004008888,0.00218648,0.0003450452,0.0006321498,0.0006704879,0.0004422794,0.002131707,0.0007676862],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000996658,"about_ca_system_score_gemma":0.001383586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005794421,"about_ca_topic_score_gemma":0.002002688,"domain_scores_codex":[0.9968988,0.002274928,0.00009005833,0.0002823311,0.0002360141,0.0002179016],"domain_scores_gemma":[0.9978078,0.00066855,0.0005939134,0.0003068611,0.0001572517,0.0004655842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9646425,0.002188003,0.004443379,0.0003775723,0.001896508,0.00006257252,0.00003613674,0.001649043,0.005200615,0.0003950408,0.003623976,0.01548467],"study_design_scores_gemma":[0.7419478,0.181907,0.04913963,0.0001167107,0.004649198,0.0002362841,0.00005386291,0.004268448,0.005623057,0.001430041,0.01054585,0.00008209809],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9749443,0.004172177,0.001944247,0.001211731,0.000616136,0.002754082,0.006866134,0.000178237,0.00731312],"genre_scores_gemma":[0.9744686,0.0008225643,0.002419353,0.001085521,0.0002418595,0.004771978,0.009569274,0.00007608037,0.006544668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006149733,"threshold_uncertainty_score":0.03252333,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01490563713339324,"score_gpt":0.3172935650436854,"score_spread":0.3023879279102922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}