{"id":"W4245632703","doi":"10.1093/neuonc/noz175.054","title":"ACTR-11. SECOND INTERIM AND 1ST MOLECULAR ANALYSIS OF THE EORTC RANDOMIZED PHASE III INTERGROUP CATNON TRIAL ON CONCURRENT AND ADJUVANT TEMOZOLOMIDE IN ANAPLASTIC GLIOMA WITHOUT 1p/19q CODELETION","year":2019,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Temozolomide; Medicine; Internal medicine; Glioma; Interim analysis; Isocitrate dehydrogenase; Hazard ratio; Oncology; IDH1; Randomized controlled trial; Confidence interval; Radiation therapy; Cancer research; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000431729,0.0002594733,0.001695765,0.0005272759,0.00003220483,0.000012897,0.00008880014,0.0001555723,0.0001476974],"category_scores_gemma":[0.0003106582,0.0001683471,0.0002679072,0.0003955403,0.0002675865,0.00004401017,0.0001004014,0.0002386479,0.000003038465],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001350367,"about_ca_system_score_gemma":0.00008733466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008739273,"about_ca_topic_score_gemma":0.000712252,"domain_scores_codex":[0.9977687,0.0006058564,0.0006953714,0.0004877698,0.0002029647,0.0002393656],"domain_scores_gemma":[0.9980575,0.001030536,0.0003993009,0.0003270816,0.00006127775,0.0001242437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5401667,0.003353713,0.02238123,0.00009769647,0.002077085,0.000489397,0.001123526,0.00008452708,0.4204779,0.0004824611,0.0001570845,0.009108719],"study_design_scores_gemma":[0.9298843,0.008261559,0.006188432,0.0001625738,0.004224164,0.00009804367,0.0001785279,0.00722388,0.04293937,0.00002668033,0.0006245673,0.0001879458],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958469,0.0004327793,0.00003547146,0.0006550989,0.0005273083,0.002247776,0.00002717936,0.00001362719,0.0002138607],"genre_scores_gemma":[0.9992182,0.0000811785,0.00001377185,0.0004204435,0.0000276707,0.0001682807,0.00004222727,0.00001937519,0.000008845864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3897175,"threshold_uncertainty_score":0.6864998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01490563713339324,"score_gpt":0.3172935650436854,"score_spread":0.3023879279102922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}