{"id":"W4245712741","doi":"10.3389/fimmu.2020.02057","title":"Antigenic Variability","year":2020,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Epitope; Immunodominance; Antigen; Biology; Virology; Antibody; Antigenic variation; Immune system; Computational biology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004463917,0.0003185615,0.0003310898,0.0002442775,0.0002439773,0.0008842894,0.0004290981,0.0003570406,0.003286788],"category_scores_gemma":[0.0005330998,0.0001439396,0.0002444175,0.0003175445,0.0003560423,0.0006219444,0.0006581424,0.0008818283,0.001112599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005260163,"about_ca_system_score_gemma":0.0002460221,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002271547,"about_ca_topic_score_gemma":0.0002250976,"domain_scores_codex":[0.9996693,0.00006799497,0.0000149624,0.0001014137,0.00009080693,0.00005552054],"domain_scores_gemma":[0.9997353,0.0000647756,0.00007218251,0.00005076921,0.00003598844,0.00004087696],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001639433,0.00004803021,0.005316389,0.0002875419,0.00006152727,0.0002688679,0.0001281435,0.00211423,0.8857748,0.04037118,0.001878821,0.06358639],"study_design_scores_gemma":[0.00005845741,0.001368199,0.03877654,0.000133618,0.0002083683,0.008879606,0.0003998937,0.01161001,0.462018,0.09689417,0.3795539,0.0000993128],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.7424018,0.02347776,0.1421938,0.002323184,0.0006288657,0.0001727156,0.001057109,0.0005475142,0.08719724],"genre_scores_gemma":[0.9738832,0.003841182,0.01014231,0.0006827905,0.0001228945,0.00006529181,0.0008103715,0.00008228014,0.01036952],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.003286788,"threshold_uncertainty_score":0.01099539,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009240679898204415,"score_gpt":0.2063776872155001,"score_spread":0.1971370073172957,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}