{"id":"W4245910152","doi":"10.1002/ange.202104014","title":"Enantioselective Total Synthesis of Berkeleyone A and Preaustinoids","year":2021,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Marine Sponges and Natural Products","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cégep de Saint-Laurent","funders":"National Natural Science Foundation of China","keywords":"Enantioselective synthesis; Alkylation; Total synthesis; Chemistry; Stereochemistry; Nonane; Convergent synthesis; Bicyclic molecule; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001104813,0.0004175006,0.0002063392,0.000260825,0.0001446895,0.0001476194,0.0001993899,0.0001485453,0.002379153],"category_scores_gemma":[0.0001038926,0.0001068423,0.0001915493,0.0002743615,0.000138995,0.0002915907,0.0003428413,0.0003847371,0.0008904685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001714252,"about_ca_system_score_gemma":0.0005479977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006016413,"about_ca_topic_score_gemma":0.001620039,"domain_scores_codex":[0.9999298,0.000009034794,0.000007840977,0.00001419996,0.00001642649,0.00002270202],"domain_scores_gemma":[0.9999425,0.000005224519,0.00001017288,0.00001118296,0.00001043401,0.00002044881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000179199,0.00006167362,0.0003798878,0.0003282076,0.00003001258,0.0003988061,0.0001364099,0.001162436,0.9705011,0.002398118,0.0004240822,0.02400014],"study_design_scores_gemma":[0.00004645319,0.0007207695,0.001584363,0.00002519892,0.00003084691,0.00054159,0.00009596773,0.0006237347,0.9711362,0.0005676459,0.02459499,0.00003245474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.942553,0.004257946,0.02400773,0.0001589405,0.0001489468,0.0002184778,0.001967392,0.0002672598,0.02642025],"genre_scores_gemma":[0.9750898,0.002422722,0.01288498,0.00005237208,0.00001301952,0.00007123194,0.0006046043,0.00003700349,0.008824172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002379153,"threshold_uncertainty_score":0.007959068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006058574328299427,"score_gpt":0.2230091057099543,"score_spread":0.2169505313816549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}