{"id":"W4246147147","doi":"10.1101/2021.02.07.21251315","title":"<i>epi</i> Liver a novel tumor specific, high throughput and cost-effective blood test for specific detection of liver cancer (HCC)","year":2021,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"International Centre for Diarrhoeal Disease Research, Bangladesh","keywords":"Hepatocellular carcinoma; DNA methylation; Liver cancer; Cancer; Oncology; Internal medicine; Medicine; Methylation; Blood test; Cancer research; Biology; Bioinformatics; Gene; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005362769,0.0005489277,0.0004315682,0.0009666783,0.0001533121,0.0005093383,0.0003017278,0.0005231445,0.002572688],"category_scores_gemma":[0.0008894988,0.0002111386,0.0002679193,0.0004225314,0.0001731623,0.0002640756,0.0003292051,0.0004058525,0.0009438076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000319619,"about_ca_system_score_gemma":0.0003491992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009283132,"about_ca_topic_score_gemma":0.002404989,"domain_scores_codex":[0.9996349,0.00008755382,0.00002568516,0.0001141239,0.0001102815,0.00002751792],"domain_scores_gemma":[0.9995884,0.00008837663,0.0001119706,0.00003580655,0.0001317481,0.00004364912],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001372008,0.0002216721,0.06095188,0.0004610352,0.0002274576,0.0004732942,0.00004191315,0.002055245,0.7634734,0.001031436,0.0237953,0.1458954],"study_design_scores_gemma":[0.0002067685,0.00216707,0.1673514,0.00007899107,0.0004052607,0.005774541,0.00004378018,0.07199008,0.707545,0.001289584,0.04300647,0.0001410703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7048492,0.009704813,0.2178652,0.004168166,0.0005032722,0.001069792,0.03281863,0.01065659,0.01836442],"genre_scores_gemma":[0.8097203,0.001716795,0.1568708,0.002752316,0.0003630446,0.000758897,0.0171651,0.0001588954,0.01049375],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002572688,"threshold_uncertainty_score":0.008606493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02302687797032307,"score_gpt":0.2605308032184127,"score_spread":0.2375039252480896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}