{"id":"W4246179640","doi":"10.1002/0471748897.ch11","title":"Susceptibility Testing","year":2005,"lang":"en","type":"other","venue":"Genetic Testing","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"North York General Hospital","funders":"","keywords":"Penetrance; Harm; Genetic testing; Heritability; Test (biology); Genetic predisposition; Medicine; Psychology; Clinical psychology; Genetics; Social psychology; Biology; Internal medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00210696,0.0005765574,0.0003367297,0.001442912,0.0006889894,0.0008692411,0.0009176041,0.0007434662,0.09456341],"category_scores_gemma":[0.005259226,0.0001108124,0.0003009918,0.0006216777,0.0003355513,0.000644405,0.001283829,0.0007388956,0.02760827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000578673,"about_ca_system_score_gemma":0.001189916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001904156,"about_ca_topic_score_gemma":0.0036977,"domain_scores_codex":[0.9991699,0.0002766642,0.00005531691,0.00009664688,0.0003040273,0.0000975541],"domain_scores_gemma":[0.9980739,0.0005190612,0.0001450132,0.0003898144,0.0005139116,0.0003582101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002252858,0.0004382283,0.01338814,0.0003068351,0.00001799397,0.002126935,0.0003492045,0.0003584944,0.002580498,0.02409104,0.2523919,0.7037255],"study_design_scores_gemma":[0.00003556332,0.0001873015,0.01072968,0.0003910819,0.00001708532,0.006946728,0.0003010782,0.0003557471,0.001993035,0.006781457,0.9722424,0.00001886964],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.01575018,0.00443186,0.02058902,0.006042065,0.0007846405,0.0009299425,0.003224879,0.001226392,0.9470211],"genre_scores_gemma":[0.1225731,0.007385039,0.0284295,0.006585029,0.0003985548,0.0008119848,0.004456336,0.000478412,0.828882],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.09456341,"threshold_uncertainty_score":0.3163461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02680863231052994,"score_gpt":0.2798203190592584,"score_spread":0.2530116867487284,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}