{"id":"W4246179640","doi":"10.1002/0471748897.ch11","title":"Susceptibility Testing","year":2005,"lang":"en","type":"other","venue":"Genetic Testing","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"North York General Hospital","funders":"","keywords":"Penetrance; Harm; Genetic testing; Heritability; Test (biology); Genetic predisposition; Medicine; Psychology; Clinical psychology; Genetics; Social psychology; Biology; Internal medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001479597,0.000330596,0.0002164694,0.00008934965,0.00007672702,0.00003363256,0.0003375504,0.0003869187,0.0007065378],"category_scores_gemma":[0.00105993,0.0003673054,0.00006782487,0.0002355056,0.0001175633,7.692897e-7,0.0002077841,0.0001705311,0.0001319645],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000709622,"about_ca_system_score_gemma":0.0004072407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001634683,"about_ca_topic_score_gemma":0.0005079267,"domain_scores_codex":[0.9983162,0.00005588175,0.000295316,0.0007601051,0.0001793815,0.0003930754],"domain_scores_gemma":[0.9986823,0.00004824721,0.000253117,0.0008111305,0.000113487,0.00009167632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000005868358,0.00006458492,0.02829894,0.0001560483,0.0001202966,0.00001040665,0.00003142629,0.001127557,0.1066453,0.000003051642,0.4467403,0.4167962],"study_design_scores_gemma":[0.0004018976,0.0001857338,0.01327018,0.0002046881,0.00007860267,0.00008625151,0.00002638427,0.0003313698,0.004593546,0.00003641898,0.9799574,0.0008275037],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.01332148,0.009393633,0.00259505,0.00006338333,0.0007670264,0.000651987,0.0001086338,0.000352433,0.9727464],"genre_scores_gemma":[0.03383445,0.00006259944,0.476915,0.0003569796,0.007177246,0.0001066031,0.000157088,0.001087196,0.4803028],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.5332171,"threshold_uncertainty_score":0.9998779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02680863231052994,"score_gpt":0.2798203190592584,"score_spread":0.2530116867487284,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}