{"id":"W4246294147","doi":"10.1002/9781119951438.eibc0507","title":"Calpain","year":2004,"lang":"en","type":"other","venue":"Encyclopedia of Inorganic and Bioinorganic Chemistry","topic":"Calpain Protease Function and Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Calpain; Proteases; Protease; Papain; Active site; Gene isoform; Chemistry; Enzyme; Biochemistry; Cysteine protease; Catalytic triad; Binding site; Intracellular; Cell biology; Biophysics; Stereochemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002419316,0.001198462,0.0004423329,0.0009603373,0.0005248709,0.001422085,0.0007371265,0.0008199868,0.09617446],"category_scores_gemma":[0.0003897277,0.0002089685,0.0003714901,0.0006574368,0.0001985125,0.0006110176,0.0008162545,0.001060094,0.05903823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005964601,"about_ca_system_score_gemma":0.0004092617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009451651,"about_ca_topic_score_gemma":0.001050437,"domain_scores_codex":[0.9997641,0.00001136631,0.00001503221,0.00006392493,0.0001025212,0.00004304797],"domain_scores_gemma":[0.9998641,0.000009185243,0.0000124867,0.00001828638,0.00006356934,0.00003240299],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007195294,0.0002410763,0.001134665,0.001640026,0.00007971801,0.001265459,0.0001006427,0.0003642609,0.4014528,0.01382374,0.1501867,0.4289913],"study_design_scores_gemma":[0.00005571153,0.00008659197,0.002177733,0.00008274398,0.00002718212,0.00139408,0.00002933818,0.0003409043,0.07251086,0.002115833,0.9211677,0.00001125336],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.05315669,0.1168677,0.03490154,0.005211694,0.01103362,0.000815199,0.02655382,0.005347901,0.7461119],"genre_scores_gemma":[0.1177734,0.03094019,0.01421538,0.001877526,0.00117644,0.0002549008,0.03584847,0.000342743,0.7975709],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.09617446,"threshold_uncertainty_score":0,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002601178838326199,"score_gpt":0.1907950494325731,"score_spread":0.1881938705942469,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}