{"id":"W4246326520","doi":"10.1016/j.bbrc.2012.06.130","title":"WITHDRAWN: Epigallocatechin-3-gallate up-regulates tumor suppressor gene expression via a reactive oxygen species-dependent down-regulation of UHRF1","year":2012,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Tea Polyphenols and Effects","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Structural Genomics Consortium","funders":"","keywords":"Suppressor; Gallate; Reactive oxygen species; Gene; Propyl gallate; Cell biology; Chemistry; Computational biology; Biology; Biochemistry; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001919541,0.0008145692,0.0005892183,0.0005342364,0.0003886507,0.0008015396,0.0006172883,0.0008262947,0.02239212],"category_scores_gemma":[0.0006074871,0.0002006515,0.0006193819,0.0004021567,0.0004844176,0.0004445532,0.0002462446,0.00221324,0.004436266],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005652223,"about_ca_system_score_gemma":0.000726101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002766442,"about_ca_topic_score_gemma":0.002767133,"domain_scores_codex":[0.9996055,0.00002658448,0.00003760375,0.00006524673,0.0001647516,0.0001003103],"domain_scores_gemma":[0.9996106,0.00009994217,0.00006630869,0.000046947,0.00008483656,0.00009148392],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002634205,0.0001007814,0.0009264863,0.0003742037,0.00008628709,0.001788161,0.00005933848,0.0001389671,0.9600884,0.001003315,0.01273224,0.02006765],"study_design_scores_gemma":[0.0004369772,0.0006020431,0.03950945,0.00004735756,0.0001812101,0.002949701,0.0003458595,0.001041249,0.872261,0.0009492429,0.08162487,0.00005099516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8051622,0.01676737,0.01403358,0.04491825,0.02487954,0.0003280282,0.03226802,0.004337042,0.05730595],"genre_scores_gemma":[0.8372514,0.004971514,0.004336153,0.004919977,0.002064434,0.0001376251,0.01348901,0.0003240653,0.1325058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02239212,"threshold_uncertainty_score":0.07490909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05698792202925393,"score_gpt":0.3424358913976531,"score_spread":0.2854479693683992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}