{"id":"W4246340264","doi":"10.1002/ange.202012956","title":"Molecularly Imprinted Polymer‐Based Smart Prodrug Delivery System for Specific Targeting, Prolonged Retention, and Tumor Microenvironment‐Triggered Release","year":2020,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Analytical chemistry methods development","field":"Chemistry","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Nanjing University; Ministry of Science and Technology of the People's Republic of China; National Natural Science Foundation of China","keywords":"Prodrug; Drug delivery; Chemistry; Tumor microenvironment; Targeted drug delivery; Pharmacology; Cancer research; Medicine; Biochemistry; Tumor cells; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001689671,0.0003690202,0.0002141655,0.0001974036,0.00009268051,0.0001719172,0.0002181021,0.0003208652,0.0006643039],"category_scores_gemma":[0.0001195194,0.0002066424,0.0001941687,0.0001008535,0.0001613091,0.000301432,0.0001756526,0.0003412861,0.0004722938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002903664,"about_ca_system_score_gemma":0.000248442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002645426,"about_ca_topic_score_gemma":0.0003408832,"domain_scores_codex":[0.9998959,0.00001276241,0.00001059002,0.00003157084,0.00002915004,0.00001988419],"domain_scores_gemma":[0.9999436,0.000007721273,0.00002324168,0.000006105968,0.000008633021,0.00001073365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002867374,0.00001894793,0.00002650615,0.00003431382,0.00000377567,0.00003250719,0.000006428746,0.0002486825,0.996147,0.0001812817,0.0001092206,0.003162675],"study_design_scores_gemma":[0.000007738414,0.00008831686,0.0001331149,0.000001175635,0.000004966727,0.00005945939,0.000001418266,0.00241716,0.9960008,0.00001234326,0.001268535,0.000004888093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8517518,0.004170883,0.1353243,0.0004439969,0.000195443,0.0002683351,0.0005926446,0.001835557,0.005417089],"genre_scores_gemma":[0.9398584,0.001134756,0.05459066,0.0001683588,0.00003581254,0.0001139923,0.000297607,0.00004393145,0.003756516],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006643039,"threshold_uncertainty_score":0.0022223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02081796993495172,"score_gpt":0.2201285951604307,"score_spread":0.1993106252254789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}