{"id":"W4246474791","doi":"10.1200/jco.2009.27.18_suppl.lba4505","title":"ESPAC-3(v2): A multicenter, international, open-label, randomized, controlled phase III trial of adjuvant 5-fluorouracil/folinic acid (5-FU/FA) versus gemcitabine (GEM) in patients with resected pancreatic ductal adenocarcinoma","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Folinic acid; Gemcitabine; Pancreatic cancer; Chemotherapy; Internal medicine; Fluorouracil; Gastroenterology; Surgery; Adenocarcinoma; Randomized controlled trial; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00333218,0.002093229,0.00170098,0.0004838119,0.0004648011,0.001103885,0.0010388,0.002261319,0.008019911],"category_scores_gemma":[0.001870459,0.0006778464,0.002101906,0.0005299652,0.001450578,0.001112576,0.0005682305,0.003331413,0.001035338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008766292,"about_ca_system_score_gemma":0.001527143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009625793,"about_ca_topic_score_gemma":0.00232055,"domain_scores_codex":[0.9989882,0.0007205206,0.00004001998,0.0001016419,0.00004706193,0.0001025781],"domain_scores_gemma":[0.9990158,0.0002239684,0.0002726947,0.00007047209,0.00005528048,0.0003617008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.978139,0.007237168,0.0008363099,0.0004683202,0.0005532994,0.00004144782,0.00004685116,0.0004389229,0.002344326,0.0001576061,0.001304444,0.008432373],"study_design_scores_gemma":[0.9647708,0.03325878,0.0007583462,0.00002166708,0.000170137,0.00003084036,0.0000121966,0.000196551,0.0002297953,0.00008752877,0.0004566692,0.000006657577],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802965,0.004681398,0.0007540787,0.001469207,0.0005550559,0.006987129,0.002430504,0.0001478311,0.00267828],"genre_scores_gemma":[0.9687027,0.003194668,0.003734268,0.003952892,0.0006966415,0.01053011,0.004346401,0.0000529216,0.004789292],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008019911,"threshold_uncertainty_score":0.0268293,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1201627371583594,"score_gpt":0.4912830903171712,"score_spread":0.3711203531588118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}