{"id":"W4246650330","doi":"10.1016/j.neuint.2021.104980","title":"The brain in flux: Genetic, physiologic, and therapeutic perspectives on transporters in the CNS","year":2021,"lang":"en","type":"editorial","venue":"Neurochemistry International","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; Agence Nationale de la Recherche","keywords":"Transporter; Neuroscience; Brain function; Function (biology); Biology; Computational biology; Excitatory amino-acid transporter; Neurochemistry; Membrane transport protein; Medicine; Bioinformatics; Gene; Neurology; Genetics; Excitatory postsynaptic potential","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008597353,0.004556462,0.003982732,0.002832193,0.002611315,0.006947571,0.003626941,0.01844431,0.007800196],"category_scores_gemma":[0.01485577,0.001158544,0.002662406,0.001331121,0.003499476,0.005771131,0.00171279,0.02287779,0.005153552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003105078,"about_ca_system_score_gemma":0.003332136,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001864544,"about_ca_topic_score_gemma":0.005577965,"domain_scores_codex":[0.9967585,0.0006546649,0.000416546,0.000423731,0.001506239,0.0002403137],"domain_scores_gemma":[0.9844971,0.007500429,0.0007009896,0.0003388269,0.004404106,0.002558557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006910806,0.00001381459,0.00001798073,0.0002674652,0.00002176233,0.0001215851,0.00001311526,0.00003567655,0.00009714896,0.0007609081,0.9925979,0.005983482],"study_design_scores_gemma":[0.0001023201,0.00007246889,0.0002349428,0.0005941318,0.00009014162,0.0004463728,0.00006009779,0.0002617315,0.0001814215,0.003242478,0.9946797,0.00003415997],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.00003151277,0.01324508,0.0001307527,0.02861711,0.9571592,0.000009374878,0.00002371031,0.00002846287,0.0007547297],"genre_scores_gemma":[0.0002577811,0.007719951,0.00006823103,0.01193918,0.9768931,0.000008794971,0.00001104126,0.00001329404,0.00308863],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.01844431,"threshold_uncertainty_score":0.04546773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02549412630255143,"score_gpt":0.34145362023348,"score_spread":0.3159594939309286,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}