{"id":"W4246895619","doi":"10.1136/jclinpath-2017-204763","title":"Rnf43","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Pathology","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"","keywords":"Frizzled; Ubiquitin ligase; Wnt signaling pathway; Ubiquitin; Cell biology; Signal transduction; Biology; LRP6; Function (biology); Cancer research; Mechanism (biology); Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002202907,0.0007346156,0.0002421788,0.0005669181,0.0006092161,0.0004284969,0.0003902034,0.0009435455,0.009764169],"category_scores_gemma":[0.000289802,0.0001998693,0.0005402978,0.0003035699,0.0002364801,0.0002889657,0.0003513664,0.0004795054,0.006965082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005898604,"about_ca_system_score_gemma":0.000344702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001451456,"about_ca_topic_score_gemma":0.001290324,"domain_scores_codex":[0.9997233,0.00002848528,0.00001493135,0.00009112996,0.00008747892,0.00005473497],"domain_scores_gemma":[0.9998748,0.00001053746,0.00002801415,0.00002139741,0.00003462622,0.00003048794],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002362818,0.00004936048,0.002110014,0.0002644401,0.00004290075,0.0014438,0.00005465676,0.00039528,0.9357778,0.002882167,0.009870772,0.04687247],"study_design_scores_gemma":[0.00002932197,0.0002351194,0.009156505,0.00006183102,0.00005097016,0.01252263,0.00004822633,0.001097358,0.5500363,0.001084535,0.4256435,0.00003384925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7582709,0.07453784,0.05233693,0.002462172,0.003191814,0.0003628811,0.01407206,0.004589567,0.09017587],"genre_scores_gemma":[0.8308771,0.01241501,0.02723964,0.001216713,0.0001866715,0.0002387941,0.01960876,0.0004517796,0.1077655],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009764169,"threshold_uncertainty_score":0,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08622201950777805,"score_gpt":0.4228467142519378,"score_spread":0.3366246947441598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}