{"id":"W4246895619","doi":"10.1136/jclinpath-2017-204763","title":"Rnf43","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Pathology","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"","keywords":"Frizzled; Ubiquitin ligase; Wnt signaling pathway; Ubiquitin; Cell biology; Signal transduction; Biology; LRP6; Function (biology); Cancer research; Mechanism (biology); Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001857277,0.00008032675,0.0003114355,0.00002239435,0.000111813,0.0000259757,0.0005107604,0.0002586637,0.00004850601],"category_scores_gemma":[0.003498802,0.00006240527,0.0002968282,0.000008274246,0.0002526036,0.000005057462,0.0001489456,0.0002896878,0.0000301978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002370552,"about_ca_system_score_gemma":0.0001113116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":7.786842e-7,"about_ca_topic_score_gemma":0.000003546875,"domain_scores_codex":[0.9987289,0.0001878205,0.0006907403,0.000144217,0.00009821781,0.0001501008],"domain_scores_gemma":[0.9981929,0.00005007129,0.0009812,0.0004732772,0.0001718093,0.0001307487],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001753902,0.0006833816,0.3394372,0.00003399527,0.0002729382,0.00154045,0.00007248756,0.000009398239,0.3941556,0.001298121,0.03082207,0.2299205],"study_design_scores_gemma":[0.003973004,0.004811245,0.3966587,0.00004198688,0.00006878431,0.001822947,0.00003174384,0.000009103316,0.08891948,0.004368756,0.4989953,0.0002989417],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866218,0.0004186826,0.0007343335,0.001036873,0.001418207,0.00004366057,0.000004245541,0.000002073104,0.009720108],"genre_scores_gemma":[0.9937801,0.0004284768,0.002176661,0.0007541147,0.002213574,9.715427e-7,0.000001794551,0.00001021674,0.0006340639],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4681733,"threshold_uncertainty_score":0.4188645,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08622201950777805,"score_gpt":0.4228467142519378,"score_spread":0.3366246947441598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}