{"id":"W4247041875","doi":"10.1017/s0958067000020169","title":"Changes in chemoreflex characteristics following acute carbonic anhydrase inhibition in humans at rest","year":2000,"lang":"en","type":"article","venue":"Experimental Physiology","topic":"Neuroscience of respiration and sleep","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Western University","funders":"","keywords":"Hypercapnia; Acetazolamide; Carbonic anhydrase; Central chemoreceptors; Peripheral chemoreceptors; Peripheral; Tidal volume; Ventilation (architecture); Hypoxia (environmental); Control of respiration; Anesthesia; Chemistry; pCO2; Respiratory minute volume; Carbonic anhydrase inhibitor; Medicine; Chemoreceptor; Internal medicine; Respiratory system; Acidosis; Oxygen; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000169344,0.0004453693,0.0006590111,0.0004456326,0.0002734147,0.0003308563,0.0001503037,0.0003831774,0.001001564],"category_scores_gemma":[0.0003861114,0.0002057448,0.0002430921,0.0001547162,0.000485284,0.0001127164,0.0001934275,0.0004066909,0.000241113],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001948263,"about_ca_system_score_gemma":0.0001127525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001393478,"about_ca_topic_score_gemma":0.001435139,"domain_scores_codex":[0.9998794,0.00001848122,0.000007597939,0.00003623899,0.00002513268,0.00003316109],"domain_scores_gemma":[0.999801,0.00003024666,0.00005358759,0.00001638177,0.00001906192,0.00007968074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01779127,0.001348365,0.3332843,0.0002255613,0.0002556812,0.007315881,0.001494442,0.0005886242,0.6100715,0.0001313094,0.0005451012,0.026948],"study_design_scores_gemma":[0.0001002,0.01137691,0.9721291,0.000009142618,0.00007356526,0.003173991,0.0002496092,0.0004258051,0.0116895,0.00005637777,0.0006941621,0.00002161992],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993635,0.0002087772,0.0001264957,0.00001346924,0.000006018357,0.000008976626,0.00005829674,0.000007803677,0.0002067371],"genre_scores_gemma":[0.999294,0.0001229723,0.00009477975,0.00003240033,0.00001029647,0.00001600922,0.0001387311,0.000003234832,0.0002875921],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001393478,"threshold_uncertainty_score":0.003350556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02828045025185423,"score_gpt":0.3110554504288098,"score_spread":0.2827750001769556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}