{"id":"W4247435032","doi":"10.1139/bcb-78-6-715","title":"Tamoxifen inhibits phorbol ester stimulated osteoclastic bone resorption: An effect mediated by calmodulin","year":2000,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Bone health and treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","keywords":"Phorbol ester; Bone resorption; Calmodulin; Chemistry; Endocrinology; Internal medicine; Phorbol; Tamoxifen; Osteoclast; Calcium; Biochemistry; Biology; Protein kinase C; Medicine; Phosphorylation; In vitro; Cancer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002330612,0.000523693,0.0005739604,0.0004090813,0.000306487,0.000339736,0.0004032881,0.0005487566,0.003138471],"category_scores_gemma":[0.0003883613,0.0003445786,0.0003638437,0.0002323899,0.0005251181,0.0003204513,0.0002807983,0.001140859,0.000705004],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000444023,"about_ca_system_score_gemma":0.0005367533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001829722,"about_ca_topic_score_gemma":0.004068524,"domain_scores_codex":[0.9997874,0.00003245487,0.00001579103,0.00001987666,0.00004837948,0.00009618463],"domain_scores_gemma":[0.9997482,0.00006867649,0.00005868909,0.00003455972,0.00002669845,0.00006330094],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001493025,0.00009782578,0.0001943996,0.00007988383,0.00001584708,0.0001019519,0.00002671933,0.00002210615,0.9945498,0.0002024984,0.0002214549,0.00299445],"study_design_scores_gemma":[0.0006058916,0.00134074,0.007693962,0.00001518224,0.00007174657,0.0004896679,0.00006641468,0.0004045459,0.9829675,0.0001193443,0.00621605,0.000008983844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9799889,0.01002084,0.003588075,0.001106486,0.0001751763,0.00009749075,0.0007889498,0.0003303651,0.003903766],"genre_scores_gemma":[0.9837492,0.005268771,0.002625016,0.0001882255,0.00008337431,0.0001261037,0.001037766,0.00005102697,0.006870574],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003138471,"threshold_uncertainty_score":0.0104993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006611624193499219,"score_gpt":0.2535104256447775,"score_spread":0.2468988014512783,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}