{"id":"W4247569210","doi":"10.24124/2010/bpgub647","title":"Dissection of U4 snRNA functional domains using in vitro reconstitution.","year":2010,"lang":"en","type":"dissertation","venue":"","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Library and Archives Canada","funders":"","keywords":"snRNP; Spliceosome; Prp24; RNA splicing; Small nuclear RNA; Ribonucleoprotein; Biology; Cell biology; Small nuclear ribonucleoprotein; Minor spliceosome; Intron; Genetics; Splicing factor; Computational biology; RNA; Gene; Non-coding RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007021999,0.0009743428,0.0004677263,0.0004954238,0.0005433658,0.0008805664,0.001287892,0.0007613741,0.00134953],"category_scores_gemma":[0.0004408926,0.0005834094,0.0007445375,0.0003517994,0.0004501029,0.0004756194,0.0009807069,0.001526047,0.001473622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001173307,"about_ca_system_score_gemma":0.0003930782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001777946,"about_ca_topic_score_gemma":0.001545156,"domain_scores_codex":[0.9995139,0.0001557275,0.00006431062,0.0000829661,0.0001068002,0.00007633711],"domain_scores_gemma":[0.9997769,0.0000666179,0.000053763,0.00003331434,0.00002876206,0.0000407144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000192898,0.00009007609,0.0002436056,0.0001728464,0.00003254825,0.0001282166,0.00009072717,0.001216908,0.992532,0.002070943,0.0003363576,0.002893035],"study_design_scores_gemma":[0.0000344893,0.0001374515,0.0004832419,0.00002833851,0.00006345314,0.0002385827,0.00005312144,0.005507342,0.9691019,0.0002980483,0.02403057,0.00002340485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8461312,0.01503567,0.1144174,0.001479842,0.0006069816,0.0004823784,0.004631555,0.001494872,0.01571998],"genre_scores_gemma":[0.9083172,0.007723055,0.06872122,0.000327949,0.00006273585,0.0003255156,0.006659416,0.0003611048,0.007501878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001777946,"threshold_uncertainty_score":0.008512974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01497252446877457,"score_gpt":0.2929876560537471,"score_spread":0.2780151315849725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}