{"id":"W4247752612","doi":"10.21203/rs.3.rs-58018/v1","title":"Endochin-like quinolone-300 and ELQ-316 inhibit Babesia bovis, B. bigemina, B. caballi and Theileria equi","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"Vector-borne infectious diseases","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; U.S. Department of Veterans Affairs; U.S. Department of Agriculture; International Development Research Centre; U.S. Department of Defense","keywords":"Biology; Babesia bigemina; Virology; Peripheral blood mononuclear cell; Microbiology; Babesiosis; In vitro; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001118792,0.0002279539,0.0001664949,0.0001492577,0.00006408487,0.0001146994,0.0001350793,0.000218173,0.001879791],"category_scores_gemma":[0.0001525212,0.00007890813,0.0001332631,0.00007499033,0.0001323904,0.0001026457,0.0000853251,0.0001685184,0.0003268752],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007725889,"about_ca_system_score_gemma":0.00009321381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006396744,"about_ca_topic_score_gemma":0.0009815902,"domain_scores_codex":[0.9999342,0.00001874221,0.000008061739,0.000009185238,0.00001755207,0.00001222896],"domain_scores_gemma":[0.9998963,0.00003265413,0.00001867839,0.000006274241,0.00002642975,0.00001965033],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000385214,0.000111983,0.0006248582,0.0001482961,0.000007856859,0.00003071248,0.00002006652,0.0001591154,0.9947089,0.00002963511,0.00007525129,0.003698139],"study_design_scores_gemma":[0.00008528589,0.005000951,0.02291487,0.00003270956,0.00003270192,0.0004363397,0.00004962244,0.001946954,0.9661782,0.00004300079,0.003271554,0.000007747146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940058,0.003348774,0.0006651032,0.00008403511,0.00001648782,0.00004063308,0.0002720641,0.00003252367,0.001534566],"genre_scores_gemma":[0.9947163,0.0009964941,0.001529944,0.00004820649,0.00001086758,0.00002516625,0.0004974797,0.000005003996,0.002170339],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001879791,"threshold_uncertainty_score":0.006288469,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04856007417258206,"score_gpt":0.3458090986729589,"score_spread":0.2972490245003769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}