{"id":"W4247918749","doi":"10.1159/000332071","title":"Alagille Syndrome","year":2012,"lang":"en","type":"book-chapter","venue":"Pediatric and adolescent medicine","topic":"Pediatric Hepatobiliary Diseases and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children; SickKids Foundation","funders":"","keywords":"Alagille syndrome; JAG1; Penetrance; Medicine; Liver disease; Pathology; Internal medicine; Gastroenterology; Phenotype; Cholestasis; Biology; Notch signaling pathway; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001645699,0.0006541616,0.001152609,0.0003957212,0.000107853,0.000007744642,0.00009713601,0.0004270234,0.002204467],"category_scores_gemma":[0.00004906039,0.000479797,0.000223861,0.00008343015,0.0001752593,0.00006659129,0.0001129079,0.0005680642,0.0004477308],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001280666,"about_ca_system_score_gemma":0.0001717797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001203896,"about_ca_topic_score_gemma":4.53417e-7,"domain_scores_codex":[0.9975423,0.00001451319,0.0006149883,0.0006133496,0.0006798389,0.0005350654],"domain_scores_gemma":[0.9978358,0.00007011957,0.0002808703,0.0005036481,0.0001004594,0.001209143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000498386,0.00126921,0.6093428,0.007377085,0.0008978002,0.005844017,0.000143475,1.65286e-7,0.000004282818,0.004880473,0.3019252,0.06781713],"study_design_scores_gemma":[0.01072402,0.001915843,0.2728693,0.001843219,0.02154563,0.003563558,0.00003885563,0.00001225024,0.00000115834,0.001746872,0.6841931,0.001546277],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.02367454,0.4416178,0.00003726514,0.003544583,0.001675887,0.002574533,0.0002696958,0.0004340223,0.5261717],"genre_scores_gemma":[0.3018785,0.2063882,0.00008041542,0.002162438,0.008381486,0.00002351453,0.0006292767,0.000199257,0.4802569],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.3822679,"threshold_uncertainty_score":0.9997654,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02196857928445838,"score_gpt":0.249351886554158,"score_spread":0.2273833072696996,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}