{"id":"W4247934501","doi":"10.1182/blood.v110.11.1183.1183","title":"Preliminary Results of CNTO 328, an Anti-Interleukin (IL)-6 Monoclonal Antibody (mAb), in Combination with Bortezomib in the Treatment of Relapsed or Refractory Multiple Myeloma.","year":2007,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital","funders":"","keywords":"Bortezomib; Multiple myeloma; Medicine; Dexamethasone; Internal medicine; Pharmacology; Oncology; Cancer research; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008886466,0.001098244,0.001594371,0.0003800736,0.0004175884,0.0006160649,0.000747391,0.0008563852,0.002763009],"category_scores_gemma":[0.0007474708,0.0003853798,0.0009827905,0.0003209136,0.0005887187,0.0005136984,0.0002656621,0.002486552,0.0006846514],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006106264,"about_ca_system_score_gemma":0.000879248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001713896,"about_ca_topic_score_gemma":0.00350882,"domain_scores_codex":[0.9996511,0.0001565755,0.00002341528,0.0000519194,0.00004309593,0.00007392217],"domain_scores_gemma":[0.9994872,0.0001153923,0.00007829517,0.00004760913,0.00003599364,0.000235579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3352152,0.1028775,0.006066015,0.001835934,0.001515043,0.0024608,0.000771101,0.00380633,0.3392085,0.0004804497,0.009766329,0.1959968],"study_design_scores_gemma":[0.1192349,0.7818072,0.02312435,0.0001026078,0.001545692,0.002475052,0.0001401725,0.001849464,0.05659282,0.0002927048,0.01278556,0.00004946196],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863986,0.006385346,0.0007803013,0.00070272,0.0002295725,0.001244316,0.0009559963,0.00009473183,0.003208334],"genre_scores_gemma":[0.9897613,0.003881444,0.001167009,0.0004599835,0.0002363695,0.0006194703,0.001374452,0.00003772247,0.002462269],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002763009,"threshold_uncertainty_score":0.00924319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02947504984335771,"score_gpt":0.3257205409892322,"score_spread":0.2962454911458745,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}