{"id":"W4248025773","doi":"10.1093/jcag/gwab002.155","title":"A157 REAL-WORLD TIGHT OBJECTIVE MONITORING WITH ADALIMUMAB LEADS TO EARLIER DOSE OPTIMIZATION AND HIGHER CLINICAL REMISSION RATES AT 12 MONTHS.","year":2021,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; McGill University Health Centre; McGill University","funders":"","keywords":"Medicine; Calprotectin; Adalimumab; Ulcerative colitis; Internal medicine; Faecal calprotectin; Inflammatory bowel disease; Crohn's disease; Gastroenterology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001919752,0.0002211088,0.0005419395,0.0002661625,0.000199406,0.0007455148,0.0002066517,0.0002806465,0.001939198],"category_scores_gemma":[0.0035059,0.000087769,0.0004723298,0.0004267333,0.000162807,0.0004329318,0.0002615419,0.0007881919,0.0003331279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002864537,"about_ca_system_score_gemma":0.0002506215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006124364,"about_ca_topic_score_gemma":0.001011586,"domain_scores_codex":[0.9987431,0.0005066911,0.0001439599,0.0002236493,0.0002679998,0.0001146513],"domain_scores_gemma":[0.9964295,0.000746427,0.001913068,0.0003554391,0.0002154828,0.0003401903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008684782,0.002439544,0.6829297,0.000317059,0.000599828,0.0001349512,0.0002298355,0.001154791,0.01097435,0.0001173526,0.001422541,0.2909953],"study_design_scores_gemma":[0.0002030645,0.007188424,0.9832339,0.00006494298,0.0002443736,0.0004899647,0.0001039321,0.001640427,0.003882895,0.000103593,0.002828121,0.00001621591],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939424,0.002870112,0.001255814,0.0002205012,0.00003475777,0.00003118274,0.0001976065,0.00004955359,0.001398105],"genre_scores_gemma":[0.9985891,0.0002378132,0.0006262466,0.00009236106,0.00002449183,0.0000140617,0.000133873,0.000005892261,0.0002761368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001939198,"threshold_uncertainty_score":0.0101527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009266323510233205,"score_gpt":0.2596308027630544,"score_spread":0.2503644792528212,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}