{"id":"W4248320863","doi":"10.2217/17435889.4.2.129","title":"Research Highlights","year":2009,"lang":"en","type":"article","venue":"Nanomedicine","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Irinotecan; Medicine; Cancer; Clinical trial; Chemotherapy; Cancer drugs; Oncology; Disease; Doxorubicin; Drug; Pharmacology; Internal medicine; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002737124,0.00006708302,0.00007953177,0.00007403656,0.00005989837,0.000007844147,0.000163807,0.00008264623,0.00008009936],"category_scores_gemma":[0.00003999019,0.00005157175,0.00002906358,0.0001227794,0.00006361212,0.000001504104,0.00002769975,0.00008842985,0.0001172708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000831903,"about_ca_system_score_gemma":0.00003814545,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008996396,"about_ca_topic_score_gemma":0.000005120057,"domain_scores_codex":[0.9992556,0.00003437055,0.000106376,0.0002057513,0.0001773217,0.0002205827],"domain_scores_gemma":[0.9995202,0.000006836879,0.00001565293,0.0002603273,0.0001245175,0.00007245834],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005255761,0.00003879883,0.0001326946,0.000001960978,0.000008254476,0.000009925897,0.00002890293,0.000001034349,0.9131625,0.000294042,0.07673232,0.00953697],"study_design_scores_gemma":[0.0005445046,0.002287301,0.009288549,0.00002673066,0.00000505896,0.00001950228,0.00008933393,0.000005656277,0.4733801,0.0004984778,0.5137362,0.0001184956],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9639609,0.001641967,0.0001900699,0.003921934,0.000178152,0.00008921409,0.000001741658,0.00001166391,0.03000435],"genre_scores_gemma":[0.9901003,0.0004262478,0.0001086723,0.001056107,0.0007336024,0.000003519636,0.0000380747,0.000004892313,0.00752861],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4397824,"threshold_uncertainty_score":0.2103035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02869616968953172,"score_gpt":0.344461473739066,"score_spread":0.3157653040495343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}