{"id":"W4248536033","doi":"10.21203/rs.2.401/v2","title":"COMMENCE Trial – Comparing hypOtherMic teMperaturEs duriNg hemiarCh surgEry A Randomized Controlled Trial of Mild vs Moderate Hypothermia on Patient Outcomes in Aortic Hemiarch Surgery with Anterograde Cerebral Perfusion","year":2019,"lang":"en","type":"preprint","venue":"Research Square","topic":"Aortic Disease and Treatment Approaches","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"University of Ottawa","keywords":"Medicine; Randomized controlled trial; Clinical endpoint; Cardiac surgery; Anesthesia; Stroke (engine); Cardiopulmonary bypass; Perioperative; Cerebral perfusion pressure; Randomization; Hypothermia; Surgery; Cerebral blood flow","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004101803,0.001585942,0.003851814,0.0004397566,0.0005683611,0.001696097,0.0009853781,0.002486556,0.008491158],"category_scores_gemma":[0.005943703,0.0005435469,0.003163501,0.000374496,0.001223636,0.001134702,0.0006522509,0.002952572,0.0008347228],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008967693,"about_ca_system_score_gemma":0.001532656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001089174,"about_ca_topic_score_gemma":0.001556906,"domain_scores_codex":[0.9967824,0.002052971,0.0002974954,0.0004683425,0.000185248,0.0002135085],"domain_scores_gemma":[0.9968534,0.001083549,0.0008073398,0.0002830939,0.0002682993,0.0007043328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9921382,0.002157242,0.0002381464,0.0006628211,0.001247374,0.00001111385,0.00001896831,0.0001116616,0.0008176561,0.0000822084,0.0002345484,0.00228006],"study_design_scores_gemma":[0.972616,0.02529141,0.0007214951,0.00005246509,0.0006468902,0.000005153471,0.000008998602,0.0001733582,0.0001474502,0.0001064765,0.000222221,0.000008065502],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.956756,0.008201509,0.001827947,0.00194337,0.002638464,0.02282673,0.001870233,0.0001800512,0.003755648],"genre_scores_gemma":[0.9627033,0.001840283,0.004043004,0.001204049,0.0008265959,0.02470445,0.0009104812,0.00002273439,0.003744913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008491158,"threshold_uncertainty_score":0.02840573,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0717160157222815,"score_gpt":0.3485503890472892,"score_spread":0.2768343733250077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}