{"id":"W4248739451","doi":"10.1161/res.121.suppl_1.457","title":"Abstract 457: Rad-deletion Provides Dual Therapeutic Benefits for the Heart","year":2017,"lang":"en","type":"article","venue":"Circulation Research","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brandon University; Manning Diversified Forest Products (Canada)","funders":"","keywords":"Medicine; Ventricle; Contractility; Cardiology; Internal medicine; Myocardial infarction; Ex vivo; Cardiac function curve; Ventricular remodeling; Heart failure; Inotrope; In vivo; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002173017,0.0007022808,0.0006821631,0.0002577369,0.0001938452,0.0004545464,0.0004178438,0.0008975599,0.00707257],"category_scores_gemma":[0.0001282628,0.000215432,0.0003481995,0.0001024702,0.0005115119,0.0002357965,0.0003202519,0.0009578418,0.002015573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002067035,"about_ca_system_score_gemma":0.0001960706,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006938626,"about_ca_topic_score_gemma":0.0001433358,"domain_scores_codex":[0.9998446,0.00002834186,0.00002226382,0.00003660117,0.0000352123,0.0000329976],"domain_scores_gemma":[0.9998574,0.00002046266,0.00004973424,0.00001517173,0.00001123511,0.00004596859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005746599,0.0001228365,0.0003334302,0.0002380361,0.00001741367,0.0002018312,0.00001057352,0.00006788687,0.9944193,0.0003329694,0.000322657,0.003358334],"study_design_scores_gemma":[0.0002823914,0.002646654,0.008043913,0.0001047658,0.0001739854,0.001967476,0.00004968296,0.0004895398,0.9688274,0.0002099968,0.01718639,0.00001793377],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.968906,0.0086871,0.007908861,0.001858253,0.0005658235,0.0001712459,0.002473616,0.0006858993,0.008743085],"genre_scores_gemma":[0.9725068,0.003619391,0.005618317,0.0006881877,0.0001469745,0.0001911391,0.002221961,0.00009415803,0.01491314],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.00707257,"threshold_uncertainty_score":0.02366012,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2294272934101574,"score_gpt":0.4399832830311504,"score_spread":0.210555989620993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}