{"id":"W4249047955","doi":"10.21203/rs.3.rs-139594/v1","title":"Morphological and Molecular Characteristics of Spheroid Formation in HT-29 and Caco-2 Colorectal Cancer Cell Lines","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Spheroid; Caco-2; Colorectal cancer; Cancer research; Cell culture; Chemistry; Biology; Cancer; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001108258,0.0001658113,0.000206017,0.000433221,0.0002275195,0.0002971783,0.00009111257,0.0003078466,0.001797682],"category_scores_gemma":[0.0001730374,0.000142704,0.0002569582,0.0004588724,0.0002081116,0.0002039906,0.0001167654,0.0003450676,0.000667483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002574039,"about_ca_system_score_gemma":0.0001858398,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003097524,"about_ca_topic_score_gemma":0.001598479,"domain_scores_codex":[0.9998895,0.00001576874,0.00001083975,0.00002268247,0.00003466278,0.00002652133],"domain_scores_gemma":[0.999779,0.00006200231,0.00003408359,0.00003065913,0.00004949005,0.00004474922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001320897,0.00002043814,0.0005812652,0.00003161672,0.0000048346,0.000186843,0.0001141605,0.00008746589,0.9974623,0.0002395031,0.0001566189,0.0009827595],"study_design_scores_gemma":[0.00002709518,0.0003133679,0.1007273,0.00001355032,0.00002843399,0.001340982,0.0003608977,0.001572326,0.8853789,0.0002201186,0.009991302,0.00002574806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9759413,0.001705657,0.006145172,0.0002538767,0.00006683607,0.00008979403,0.006230501,0.000214664,0.009352212],"genre_scores_gemma":[0.9753122,0.001111615,0.005612798,0.0001030152,0.00001378907,0.00009772673,0.007749666,0.00005502111,0.009943999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003097524,"threshold_uncertainty_score":0.006159008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04926388843021701,"score_gpt":0.379117462566487,"score_spread":0.32985357413627,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}