{"id":"W4249219855","doi":"10.1158/1538-7445.am2019-4389","title":"Abstract 4389: Post-translational modifications of histone demethylase JMJD1A in prostate cancer cells","year":2019,"lang":"en","type":"article","venue":"Cancer Research","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Prostate cancer; Demethylase; Cancer research; Histone; Ubiquitin; Androgen receptor; Chemistry; Interactome; Cancer; EZH2; Chromatin immunoprecipitation; Biology; Medicine; Biochemistry; Internal medicine; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001436029,0.0003162897,0.0002967338,0.0003042267,0.0003802019,0.0003358095,0.0002826139,0.0002656998,0.003195252],"category_scores_gemma":[0.0001198425,0.0001317418,0.0002881028,0.0005190792,0.0001259632,0.0001848221,0.0001794227,0.0006857842,0.001497137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003467038,"about_ca_system_score_gemma":0.0002843449,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001747126,"about_ca_topic_score_gemma":0.001380369,"domain_scores_codex":[0.9998534,0.0000112545,0.00001460401,0.00003850875,0.00005529059,0.00002687972],"domain_scores_gemma":[0.9999464,0.000007013583,0.00001414125,0.000007746267,0.00001196659,0.00001278535],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001836273,0.00004059066,0.0006725402,0.0001412016,0.00001811063,0.0002191032,0.00001853362,0.00004714886,0.9917567,0.0001984528,0.001728091,0.004976029],"study_design_scores_gemma":[0.00004264219,0.0002414674,0.04432579,0.00001786522,0.00004514939,0.001073432,0.00004182754,0.001102484,0.9189789,0.0001553658,0.03395813,0.00001700896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9106979,0.02700754,0.01296439,0.001932432,0.002078705,0.0002348168,0.02188936,0.0008879504,0.02230703],"genre_scores_gemma":[0.9317952,0.01125315,0.008392801,0.0004901096,0.0001888895,0.0001677473,0.01809805,0.00007733807,0.02953673],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003195252,"threshold_uncertainty_score":0.0106892,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08258141192698826,"score_gpt":0.4642664800740971,"score_spread":0.3816850681471088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}