{"id":"W4249376235","doi":"10.3410/f.1017071.207413","title":"Faculty Opinions recommendation of RhoA and zeta PKC control distinct modalities of LFA-1 activation by chemokines: critical role of LFA-1 affinity triggering in lymphocyte in vivo homing.","year":2004,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"RHOA; Chemokine; In vivo; Homing (biology); Lymphocyte homing receptor; Lymphocyte; Modalities; Chemokine receptor; Cell biology; Immunology; Chemistry; Cancer research; Medicine; Biology; Cell adhesion; Cell; Signal transduction; Biochemistry; Inflammation; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001136712,0.001948784,0.001394466,0.003856602,0.0006503846,0.002255044,0.002350226,0.001551971,0.02972895],"category_scores_gemma":[0.008824554,0.0005213908,0.001446821,0.004924786,0.0002269198,0.0008698695,0.0008968235,0.001364983,0.02771773],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001586556,"about_ca_system_score_gemma":0.003192166,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02819495,"about_ca_topic_score_gemma":0.04458231,"domain_scores_codex":[0.9985352,0.00025539,0.0001998153,0.0003339754,0.0005157441,0.0001598135],"domain_scores_gemma":[0.9960198,0.001422027,0.0004725645,0.0006022707,0.001136584,0.0003467988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002506494,0.00007016707,0.004514552,0.001688783,0.0001441577,0.0000528753,0.0000219662,0.0007365247,0.0003772083,0.0004049957,0.979518,0.01222007],"study_design_scores_gemma":[0.0005786474,0.00005273035,0.02620555,0.0004472165,0.0002602292,0.0001352001,0.00008552289,0.002394384,0.001890806,0.0007930463,0.9671074,0.00004930229],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"commentary","genre_scores_codex":[0.0009268445,0.0002963564,0.0001292958,0.0002111824,0.00005128049,0.00002418805,0.9965075,0.000360094,0.001493402],"genre_scores_gemma":[0.002143702,0.0002199033,0.0005448072,0.00007511913,0.00001652044,0.0001003602,0.9950047,0.00005642654,0.001838524],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.02972895,"threshold_uncertainty_score":0.09945327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01431545692607838,"score_gpt":0.3058488993142017,"score_spread":0.2915334423881233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}