{"id":"W4249401145","doi":"10.1182/blood.v126.23.3352.3352","title":"Transcriptional Induction of Transferrin Receptors By Heme in Erythroid Cells","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Iron Metabolism and Disorders","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Transferrin receptor; Transferrin; Endosome; Endocytic cycle; Endocytosis; Biology; Cell biology; Receptor; Asialoglycoprotein receptor; Molecular biology; Biochemistry; Intracellular; In vitro; Hepatocyte","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001179123,0.0001613909,0.0001863012,0.000203255,0.0001252896,0.0002456162,0.0001270038,0.0001704329,0.001556862],"category_scores_gemma":[0.000148798,0.0001055654,0.0001883914,0.0001099114,0.0001364919,0.00008129893,0.0002568306,0.0004496374,0.0007123869],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003324274,"about_ca_system_score_gemma":0.0001103522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006925589,"about_ca_topic_score_gemma":0.0006292585,"domain_scores_codex":[0.9998428,0.00003231392,0.00001463583,0.00003373364,0.00003855633,0.00003803627],"domain_scores_gemma":[0.9998375,0.00004054177,0.00002300014,0.00002678832,0.00003632405,0.00003576185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000541706,0.000008899351,0.0001250856,0.00001800661,0.000001175505,0.00003470342,0.00001443682,0.00001369832,0.9988494,0.00008233126,0.00006249959,0.0007355565],"study_design_scores_gemma":[0.00002539888,0.0002074532,0.01106489,0.00001179604,0.00001124895,0.0002702255,0.00008362609,0.001094533,0.9792354,0.00008821016,0.007900076,0.000007174435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831617,0.002790755,0.007203899,0.0002133362,0.0000928489,0.00006633651,0.001811561,0.0002391306,0.004420509],"genre_scores_gemma":[0.9886282,0.0004733523,0.002080295,0.0001046053,0.000023288,0.00004666849,0.001704002,0.00004892398,0.006890631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001556862,"threshold_uncertainty_score":0.005208254,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.021024710804407,"score_gpt":0.2401791488718336,"score_spread":0.2191544380674266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}