{"id":"W4249995199","doi":"10.1111/bjd.19509","title":"A head‐to‐head comparison of ixekizumab vs. guselkumab in patients with moderate‐to‐severe plaque psoriasis: 24‐week efficacy and safety results from a randomized, double‐blinded trial*","year":2020,"lang":"en","type":"article","venue":"British Journal of Dermatology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"SKiN Health; Probity Medical Research; Dermatrials Research; Dalhousie University; Guenther Dermatology Research Centre","funders":"Eli Lilly and Company","keywords":"Ixekizumab; Medicine; Psoriasis; Double blinded; Randomized controlled trial; Dermatology; Plaque psoriasis; Head (geology); Physical therapy; Internal medicine; Alternative medicine; Placebo; Psoriatic arthritis; Secukinumab; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002328255,0.001654301,0.003861575,0.0004313177,0.0004219398,0.001497006,0.0007416716,0.001771799,0.006096054],"category_scores_gemma":[0.002159049,0.0008096559,0.002821881,0.0004053579,0.0009890618,0.001139195,0.0003468769,0.002709865,0.0009925634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005682473,"about_ca_system_score_gemma":0.0009054651,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007592638,"about_ca_topic_score_gemma":0.001405308,"domain_scores_codex":[0.9987519,0.000719497,0.00009850883,0.0002010734,0.00009947042,0.000129648],"domain_scores_gemma":[0.9989385,0.0003994193,0.0002363879,0.0001052727,0.00008624965,0.0002341936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9838827,0.00331472,0.0001613971,0.0005091697,0.001125155,0.00001503986,0.00003014313,0.0001210769,0.001793896,0.00004330456,0.0004364306,0.008566992],"study_design_scores_gemma":[0.9415933,0.05533475,0.001034792,0.0000360959,0.0008765254,0.0000193354,0.0000177474,0.0002455898,0.000378993,0.00009937328,0.0003490413,0.00001435798],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9786909,0.01279348,0.0009272077,0.0007151624,0.001180884,0.002397534,0.0009840623,0.0001621243,0.002148615],"genre_scores_gemma":[0.9875309,0.00434937,0.001087092,0.0007614584,0.0007250641,0.002113539,0.0005570463,0.00003968513,0.00283581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006096054,"threshold_uncertainty_score":0.02039337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03110196277926942,"score_gpt":0.2690927002085634,"score_spread":0.237990737429294,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}