{"id":"W4249995199","doi":"10.1111/bjd.19509","title":"A head‐to‐head comparison of ixekizumab vs. guselkumab in patients with moderate‐to‐severe plaque psoriasis: 24‐week efficacy and safety results from a randomized, double‐blinded trial*","year":2020,"lang":"en","type":"article","venue":"British Journal of Dermatology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"SKiN Health; Probity Medical Research; Dermatrials Research; Dalhousie University; Guenther Dermatology Research Centre","funders":"Eli Lilly and Company","keywords":"Ixekizumab; Medicine; Psoriasis; Double blinded; Randomized controlled trial; Dermatology; Plaque psoriasis; Head (geology); Physical therapy; Internal medicine; Alternative medicine; Placebo; Psoriatic arthritis; Secukinumab; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003230731,0.0003500703,0.002623731,0.0002962601,0.000137225,0.00004293013,0.0003475432,0.0004287334,0.00004348176],"category_scores_gemma":[0.0005213563,0.0003234338,0.0001992221,0.0003473292,0.0001770982,0.0001763693,0.0001028829,0.0005257045,0.0000313063],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005771284,"about_ca_system_score_gemma":0.0002418266,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005134156,"about_ca_topic_score_gemma":0.000677616,"domain_scores_codex":[0.9957789,0.001099798,0.002024868,0.0004812192,0.0001471676,0.000468092],"domain_scores_gemma":[0.9974713,0.0009117014,0.0009166161,0.0002151128,0.0003000363,0.0001851977],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9697051,0.001367308,0.003558994,0.00002430175,0.001144331,0.0003838025,0.003080602,0.000160422,0.0001065702,0.00001953809,0.002040604,0.01840844],"study_design_scores_gemma":[0.9677833,0.002403043,0.02337218,0.0005491926,0.0004887262,0.001366474,0.0002437765,0.00001589586,0.00250727,0.00003819267,0.0008807631,0.0003512344],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916859,0.002975749,0.0002556892,0.002381314,0.0006110336,0.001617688,0.0003767171,0.00002360175,0.00007225347],"genre_scores_gemma":[0.9981197,0.0002865162,0.0009519668,0.0003216885,0.0000621168,0.00003471223,0.0001742188,0.00003262343,0.00001652822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01981319,"threshold_uncertainty_score":0.9999218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03110196277926942,"score_gpt":0.2690927002085634,"score_spread":0.237990737429294,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}