{"id":"W4250070835","doi":"10.1007/978-0-387-73657-0_202","title":"Inhibition of pathogenically-related morphologic transition in Candida albicans by disrupting Cdc42 binding to its effectors","year":2009,"lang":"en","type":"article","venue":"Advances in experimental medicine and biology","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Waterloo; Biotechnology Research Institute","funders":"","keywords":"Candida albicans; Effector; CDC42; Transition (genetics); Chemistry; Cell biology; Microbiology; Biology; Biochemistry; Signal transduction; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001331898,0.000441745,0.0002246911,0.000286288,0.0004671051,0.0004911023,0.0004233666,0.0003219883,0.001496507],"category_scores_gemma":[0.0001642685,0.0002403161,0.0002636678,0.0002462192,0.0002571809,0.0001607255,0.0002709189,0.0008923745,0.0003654658],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004117148,"about_ca_system_score_gemma":0.0004459352,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001594016,"about_ca_topic_score_gemma":0.001693683,"domain_scores_codex":[0.9998016,0.00003671034,0.00001690886,0.00002375579,0.00006183458,0.00005921029],"domain_scores_gemma":[0.9999031,0.00002327003,0.00001694299,0.00001683745,0.0000129338,0.00002683101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001796697,0.00005914845,0.00006723524,0.00001925325,0.000003936987,0.00005629266,0.000009903965,0.00008248029,0.9984412,0.0002451738,0.0000426886,0.0007930233],"study_design_scores_gemma":[0.00001200955,0.0000648006,0.001048931,0.0000026004,0.000005270556,0.0001170711,0.00002141354,0.0007093993,0.9969938,0.00004185609,0.0009800442,0.000002841967],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933809,0.001395759,0.002006612,0.0001855444,0.00004996914,0.000027268,0.0002502675,0.00007636115,0.002627422],"genre_scores_gemma":[0.9960977,0.0005017827,0.001110108,0.00004147638,0.000006565948,0.00002156148,0.0003000559,0.00001562684,0.001905135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001594016,"threshold_uncertainty_score":0.005006254,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01802558947874934,"score_gpt":0.3555253432801604,"score_spread":0.3374997538014111,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}