{"id":"W4250111159","doi":"10.1515/iupac.76.0286","title":"Maximum Tolerated Dose (MTD)","year":2016,"lang":"en","type":"dataset","venue":"IUPAC Standards Online","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Glossary; Toxicokinetics; Hazard; Toxicology; Medicine; Computer science; Pharmacology; Chemistry; Biology; Linguistics; Philosophy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001150569,0.001074905,0.002188149,0.003109323,0.0003469296,0.00171407,0.001954895,0.001149707,0.07816815],"category_scores_gemma":[0.01019011,0.0004489811,0.00155026,0.005205114,0.0002970916,0.001596,0.0008560719,0.001912624,0.03967369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001645129,"about_ca_system_score_gemma":0.001613806,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009848605,"about_ca_topic_score_gemma":0.01318334,"domain_scores_codex":[0.9988894,0.0001970398,0.0002798255,0.0003340728,0.0002330961,0.00006649444],"domain_scores_gemma":[0.9957736,0.001783321,0.0009538334,0.0005681838,0.0007448168,0.0001763356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006780176,0.00005467859,0.003585484,0.006935968,0.0003081,0.00007892873,0.00003805001,0.001330499,0.0002959744,0.001405378,0.9553311,0.02995775],"study_design_scores_gemma":[0.0005817449,0.00008748651,0.01059233,0.002104704,0.0002624418,0.0003044727,0.00004211876,0.0005759645,0.0005129527,0.004545346,0.9803354,0.00005518847],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0002639275,0.0008343134,0.0002295122,0.00009513422,0.00003440099,0.00003434834,0.9963766,0.0001850325,0.001946777],"genre_scores_gemma":[0.00227932,0.00132531,0.0009351945,0.0003603739,0.0000358562,0.0002663871,0.9929774,0.0001403937,0.001679767],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.07816815,"threshold_uncertainty_score":0.2614985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01128805212490874,"score_gpt":0.3756922389225381,"score_spread":0.3644041867976294,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}