{"id":"W4250329191","doi":"10.1139/o00-009","title":"Transcriptional repression of TRH promoter function by T3: analysis by in vivo gene transfer","year":2000,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Biology; Gene isoform; Luciferase; Endocrinology; Internal medicine; Transcription factor; Xenopus; Thyrotropin-releasing hormone; Transcription (linguistics); Molecular biology; Gene; Transfection; Hormone; Genetics; Medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002719417,0.0004142521,0.0001970589,0.0002310537,0.0001375545,0.0003047705,0.0004106862,0.000382133,0.001909841],"category_scores_gemma":[0.0001791408,0.0001398043,0.0003721033,0.0001481534,0.0003994354,0.0002290703,0.0001628649,0.0008667297,0.0005959009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000374888,"about_ca_system_score_gemma":0.0001713636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006312269,"about_ca_topic_score_gemma":0.0005682898,"domain_scores_codex":[0.9998573,0.00003016148,0.00001346603,0.00004245738,0.00002857171,0.00002796268],"domain_scores_gemma":[0.9997993,0.00006796024,0.00006063394,0.00002663238,0.00001795278,0.00002741041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001728575,0.00001003773,0.00002964112,0.000009991344,0.000001199218,0.00001131586,0.000007124527,0.00001750984,0.9995154,0.00008810316,0.000006858573,0.0002856051],"study_design_scores_gemma":[0.000006775814,0.0001289156,0.0003626178,0.000002562583,0.000008958406,0.00008255103,0.000009119427,0.000490569,0.9979061,0.00004298494,0.0009565933,0.00000235997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8796619,0.001344592,0.1143215,0.0003159229,0.0001336051,0.0001109659,0.000899757,0.0004855613,0.002726291],"genre_scores_gemma":[0.9524719,0.002094639,0.03539263,0.0001286153,0.0000390473,0.0001825612,0.001403065,0.0002602072,0.008027247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001909841,"threshold_uncertainty_score":0.006389081,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004661212149379249,"score_gpt":0.2115559851380691,"score_spread":0.2068947729886899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}