{"id":"W4250334653","doi":"10.21203/rs.3.rs-48885/v1","title":"Partnering with Patients to Get Better Outcomes with Chimeric Antigen Receptor T-cell Therapy: Towards Meaningful Patient Engagement in Early Phase Trials","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"Mental Health and Patient Involvement","field":"Health Professions","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Ottawa Hospital","funders":"Government of Canada","keywords":"Chimeric antigen receptor; Phase (matter); Medicine; Immunology; Immunotherapy; Immune system; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.04391999,0.0004092745,0.0007023558,0.0003558109,0.001320732,0.005753186,0.0007224663,0.002778646,0.01814496],"category_scores_gemma":[0.07758578,0.0002462364,0.0007412159,0.0005479943,0.001298474,0.003170905,0.005013093,0.004424988,0.003361209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001122657,"about_ca_system_score_gemma":0.008785224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004290305,"about_ca_topic_score_gemma":0.001008465,"domain_scores_codex":[0.9606659,0.03418805,0.0004710837,0.0006736993,0.002223486,0.001777592],"domain_scores_gemma":[0.9551535,0.02723429,0.003697361,0.002301119,0.002234085,0.009379582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006222513,0.004114731,0.02118887,0.001594797,0.0004351357,0.0002695328,0.003924738,0.001485549,0.002331802,0.03154239,0.1201153,0.8067747],"study_design_scores_gemma":[0.01767726,0.01373425,0.0645583,0.006358971,0.000850262,0.001016767,0.0101394,0.01336718,0.01306965,0.3827184,0.4762309,0.0002786194],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.2938793,0.0113135,0.07050187,0.4552964,0.005125042,0.00469345,0.002116422,0.0008539917,0.15622],"genre_scores_gemma":[0.8674803,0.005169881,0.06053896,0.04105318,0.002133556,0.005647938,0.001152569,0.0003290348,0.01649463],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.04391999,"threshold_uncertainty_score":0.2322739,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5036321546718862,"score_gpt":0.5456262072843968,"score_spread":0.04199405261251066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}