{"id":"W4250462636","doi":"10.1016/j.bpj.2015.11.2190","title":"Effects of Salt on the Stability of a G-Quadruplex from the Human c-MYC Promoter","year":2016,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"G-quadruplex; Chemistry; Counterion; Potassium; Ion; Thermal stability; Salt (chemistry); Crystallography; Melting temperature; Biophysics; Stereochemistry; Biochemistry; DNA; Physical chemistry; Materials science; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006785234,0.0003949823,0.0004804738,0.0002368599,0.000369526,0.0008120993,0.0005186628,0.0005776765,0.002149906],"category_scores_gemma":[0.001893006,0.0004652024,0.0002932191,0.0002594611,0.0009328995,0.0005889864,0.0005765299,0.0009711814,0.000442155],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006446354,"about_ca_system_score_gemma":0.0005277294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002084184,"about_ca_topic_score_gemma":0.001837244,"domain_scores_codex":[0.9992751,0.0002107312,0.0001450904,0.000119122,0.0001584815,0.00009149247],"domain_scores_gemma":[0.9983053,0.0007339933,0.000279427,0.0001410693,0.0002750097,0.0002652051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002261818,0.0001386867,0.0006187228,0.00007861382,0.00005543942,0.00009820591,0.0001739235,0.0003400978,0.9944612,0.0001423833,0.00008721021,0.001543692],"study_design_scores_gemma":[0.00005988542,0.0003918541,0.001736009,0.000007390924,0.00003091434,0.00007719557,0.00004871055,0.0009300426,0.9959953,0.0000832358,0.0006218111,0.00001771331],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983115,0.0003994807,0.0003812595,0.0001052015,0.00004622975,0.00001193146,0.0001786777,0.00002544229,0.0005402889],"genre_scores_gemma":[0.998172,0.0001869371,0.0004318347,0.00007405915,0.00001809825,0.00001104343,0.0004161676,0.00004195714,0.0006477802],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002149906,"threshold_uncertainty_score":0.007192135,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009130735050184283,"score_gpt":0.2333931172170319,"score_spread":0.2242623821668476,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}