{"id":"W4250464594","doi":"10.1107/s010876732108990x","title":"Repurposing an ancient protein core structure: structural studies on FmtA, a novel esterase of <i>Staphylococcus aureus</i>","year":2021,"lang":"en","type":"article","venue":"Acta Crystallographica Section A Foundations and Advances","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Staphylococcus aureus; Repurposing; Esterase; Core (optical fiber); Microbiology; Biology; Materials science; Biochemistry; Enzyme; Genetics; Bacteria; Composite material; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009526146,0.0003239969,0.0002112415,0.0001204393,0.0002188209,0.000267594,0.0002921996,0.0003043631,0.0007673179],"category_scores_gemma":[0.0001679838,0.0001055215,0.0003071744,0.0001412665,0.0001724781,0.0002838468,0.0001369248,0.0007795666,0.0003192505],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003564337,"about_ca_system_score_gemma":0.0001992521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002309068,"about_ca_topic_score_gemma":0.0025251,"domain_scores_codex":[0.9999523,0.000007834142,0.000002131572,0.00001160584,0.00001546931,0.00001062289],"domain_scores_gemma":[0.9999561,0.00001057765,0.00001085526,0.000002243471,0.000006771136,0.00001342466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002945426,0.00009474492,0.001982538,0.0003094688,0.0000270523,0.001141282,0.0001787439,0.004227062,0.9812365,0.0008457495,0.0008210606,0.008841366],"study_design_scores_gemma":[0.0001528116,0.001398847,0.03569062,0.000177276,0.000245416,0.004952592,0.0006181471,0.06475504,0.8486287,0.0009689688,0.04231925,0.0000923121],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880754,0.004925766,0.003918258,0.0003367264,0.00005109716,0.0000277087,0.000319385,0.00008299948,0.00226262],"genre_scores_gemma":[0.9865295,0.003434464,0.007706934,0.000167004,0.00003829476,0.00001291596,0.001009127,0.00001923431,0.001082535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002309068,"threshold_uncertainty_score":0.004591286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02552537228386439,"score_gpt":0.2963777298484284,"score_spread":0.270852357564564,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}