{"id":"W4250467159","doi":"10.1016/j.chom.2007.08.002","title":"Host-Mediated Inflammation Disrupts the Intestinal Microbiota and Promotes the Overgrowth of Enterobacteriaceae","year":2007,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":509,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"","keywords":"Biology; Enterobacteriaceae; Inflammation; Microbiology; Host (biology); Gut flora; Bacteria; Escherichia coli; Immunology; Ecology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004471618,0.000186364,0.0001457458,0.00003556963,0.0001518603,0.00003780027,0.000255298,0.0001327089,0.00001758726],"category_scores_gemma":[0.00005479246,0.000117246,0.00006527978,0.0001085286,0.0002618551,0.000005796993,0.0002088821,0.0001546156,0.0000122171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001583229,"about_ca_system_score_gemma":0.00006580383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005973328,"about_ca_topic_score_gemma":0.0001290093,"domain_scores_codex":[0.9989609,0.00006971658,0.0003274579,0.0002690703,0.00005844837,0.000314445],"domain_scores_gemma":[0.9992389,0.00005460524,0.000200236,0.0003491963,0.00009536395,0.00006169523],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009962704,0.00005229079,0.008338053,0.00007661455,0.00001799817,0.000001401208,0.0004841722,1.257554e-7,0.9900211,0.0000143562,0.0006671366,0.0002271349],"study_design_scores_gemma":[0.0004345431,0.0002255463,0.1272134,0.00004410982,0.00002202912,0.00005723038,0.0001766052,0.000002059889,0.8572525,0.000004329204,0.01443887,0.0001287559],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973212,0.001131285,0.0002217924,0.0004471442,0.0001347874,0.0004199571,0.00004368246,0.000009479387,0.000270649],"genre_scores_gemma":[0.9985495,0.0002800972,0.0002543851,0.0002920631,0.0001516933,0.000004173401,0.0001573714,0.00002194207,0.0002887288],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1327686,"threshold_uncertainty_score":0.4781151,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004682348023288543,"score_gpt":0.2223735402659965,"score_spread":0.217691192242708,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}