{"id":"W4250532624","doi":"10.1385/1-59259-250-3:193","title":"Microinjection of myo-Inositol(1,4,5)trisphosphate and Other Calcium-Mobilizing Agents into Intact Adherent Cells","year":2003,"lang":"en","type":"book-chapter","venue":"Humana Press eBooks","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Leicester; Ryerson University","keywords":"Inositol; Second messenger system; Diacylglycerol kinase; Phosphatidylinositol; Microinjection; Inositol trisphosphate; Cell biology; Intracellular; Chemistry; Biochemistry; Receptor; Calcium in biology; Population; Biology; Signal transduction; Protein kinase C","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001441467,0.0004365267,0.0007787427,0.0001925478,0.00009263126,0.00003038603,0.000085993,0.0003652303,0.0003906917],"category_scores_gemma":[0.00001443016,0.0004008858,0.0002091645,0.00000846146,0.0001804777,0.00003038959,0.00007107109,0.0003487437,0.00002531767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001061148,"about_ca_system_score_gemma":0.00005685472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005464167,"about_ca_topic_score_gemma":0.00001319773,"domain_scores_codex":[0.998339,0.00003786041,0.0005664127,0.0004987828,0.0003051105,0.0002528082],"domain_scores_gemma":[0.9987666,0.00006630764,0.000380385,0.0004785633,0.0001189187,0.0001892061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00418199,0.001169373,0.001518503,0.02527331,0.01003179,0.0004070413,0.01220174,0.00001810035,0.2907832,0.1100342,0.2401991,0.3041816],"study_design_scores_gemma":[0.00212321,0.0004719191,0.00006863649,0.001705725,0.000927572,0.00001972349,0.00004502479,0.00003082655,0.2185057,0.000701208,0.7749417,0.0004586486],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.01455829,0.01420221,0.00006989366,0.000008958419,0.0007842351,0.001308377,0.00003539549,0.0001069105,0.9689257],"genre_scores_gemma":[0.03608464,0.0009685428,0.0006899872,0.001356375,0.0003329976,0.00007184731,0.00004914572,0.0002308588,0.9602156],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.5347427,"threshold_uncertainty_score":0.9998443,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07070987623630175,"score_gpt":0.2939377049540797,"score_spread":0.2232278287177779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}