{"id":"W4250569156","doi":"10.21203/rs.3.rs-147798/v1","title":"Angiopoietin 1 release from Human Neutrophils is Independent from Neutrophil Extracellular Traps (NETs)","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Montreal Heart Institute","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Institut de Cardiologie de Montréal","keywords":"Neutrophil extracellular traps; S100A9; Calprotectin; Myeloperoxidase; Neutrophil elastase; S100A8; Inflammation; Elastase; Innate immune system; Immunology; Chemistry; Proteinase 3; Extracellular; Fibrinogen; Immune system; Medicine; Internal medicine; Biochemistry; Enzyme; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001823955,0.0001899388,0.000182601,0.0001396611,0.00008270155,0.0002146543,0.00008270448,0.0001686117,0.001328583],"category_scores_gemma":[0.000246366,0.0000792455,0.0001751119,0.00008062793,0.0001123717,0.000132916,0.000182407,0.0002287303,0.0002442361],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007475521,"about_ca_system_score_gemma":0.00008784896,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002533239,"about_ca_topic_score_gemma":0.0002489855,"domain_scores_codex":[0.9998595,0.00003850395,0.00001308452,0.00003157559,0.00002965519,0.00002765136],"domain_scores_gemma":[0.9998664,0.00002871376,0.0000382154,0.0000103967,0.00001575339,0.00004049676],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005627643,0.0001743588,0.02114002,0.0002799176,0.00004802669,0.000638163,0.0001104792,0.000052729,0.9613281,0.00006833929,0.0002564292,0.01027575],"study_design_scores_gemma":[0.0006986537,0.00623752,0.6040988,0.0000765135,0.0001522932,0.005605652,0.0002926856,0.002104718,0.375711,0.0001842596,0.004816575,0.00002130393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950414,0.003426862,0.0004889742,0.00006336579,0.00002680437,0.00004417524,0.000299152,0.00001015262,0.0005991979],"genre_scores_gemma":[0.9979565,0.0005246555,0.0004017779,0.00003944094,0.00003097143,0.00003729993,0.0004487357,0.000001388855,0.0005592644],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001328583,"threshold_uncertainty_score":0.00444454,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05851656258157356,"score_gpt":0.3379848099685836,"score_spread":0.27946824738701,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}