{"id":"W4250615808","doi":"10.32920/ryerson.14657898.v1","title":"The acyltransferase lycat controls specific phosphoinositides and related membrane traffic and hormone receptor signaling","year":2021,"lang":"en","type":"preprint","venue":"","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Toronto Metropolitan University","funders":"","keywords":"Phosphatidylinositol; Cell biology; Phosphorylation; Biochemistry; Acyltransferase; Kinase; Pi; Signal transduction; Biology; Gene silencing; Receptor; Chemistry; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001336902,0.000368496,0.0002353772,0.0002371057,0.000243496,0.0006726402,0.000259314,0.0004620399,0.001270199],"category_scores_gemma":[0.0002111631,0.0002117969,0.0003355263,0.0002431635,0.0004290209,0.0003772943,0.0004142282,0.0008416697,0.0007580835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007854881,"about_ca_system_score_gemma":0.0003832289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001197737,"about_ca_topic_score_gemma":0.001373919,"domain_scores_codex":[0.999782,0.00001935089,0.00001692405,0.00006709197,0.00005837852,0.00005626627],"domain_scores_gemma":[0.9998771,0.0000157008,0.00003823149,0.00001356874,0.00002260012,0.00003276159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001089144,0.00001096065,0.0003465708,0.00002644981,0.000003207765,0.0000475586,0.00001717008,0.00006850999,0.9980265,0.0002884004,0.00006529475,0.0009904339],"study_design_scores_gemma":[0.00001407427,0.00007729848,0.004175506,0.000006568103,0.00001322691,0.0001315322,0.00004904393,0.00206372,0.9884837,0.0001518275,0.004824599,0.000009008965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9749291,0.005070929,0.01063002,0.0005609494,0.0001660284,0.00008200092,0.001479919,0.0005544099,0.006526635],"genre_scores_gemma":[0.9910274,0.001198259,0.001855418,0.0001169834,0.00001297131,0.00005620522,0.0007958363,0.00005328345,0.004883565],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001270199,"threshold_uncertainty_score":0.005699098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007126655445380646,"score_gpt":0.2032521297827404,"score_spread":0.1961254743373597,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}