{"id":"W4250754662","doi":"10.1182/blood.v120.21.962.962","title":"Treatment of Severe Relapsing-Remitting Multiple Sclerosis with High-Dose Immunosuppressive Therapy and Autologous Hematopoietic Cell Transplantation: 2-Year Follow-up Results of the HALT MS Clinical Trial (Immune Tolerance Network: ITN033AI)","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"Polyomavirus and related diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; Multiple sclerosis; Transplantation; Internal medicine; Adverse effect; Prednisone; Surgery; Hematopoietic stem cell transplantation; Clinical endpoint; Busulfan; Clinical trial; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002165118,0.0002162445,0.0006237763,0.00002732188,0.0001380864,0.00000842432,0.00009608352,0.0001960664,0.00001181313],"category_scores_gemma":[0.00006502932,0.0001213348,0.0002249532,0.0001780915,0.0002251459,0.00006881756,0.00001861067,0.0001599255,0.00000154248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001292323,"about_ca_system_score_gemma":0.0001189729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00022414,"about_ca_topic_score_gemma":0.000007072007,"domain_scores_codex":[0.9982421,0.0001935531,0.0007554851,0.0002474618,0.0002433335,0.0003180127],"domain_scores_gemma":[0.9983976,0.0004523315,0.0005062095,0.000435995,0.00008398449,0.0001239085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.4421089,0.01949394,0.4881978,0.0005848769,0.002814463,0.00008905325,0.01216312,0.0004028443,0.02304101,0.0001085178,0.0002890194,0.01070645],"study_design_scores_gemma":[0.396742,0.003929026,0.5476522,0.001235829,0.002011712,0.0001413786,0.0002220228,0.00003898258,0.04768932,0.00001052245,0.0001005239,0.0002265272],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816473,0.01638494,0.00000418375,0.0001115387,0.0005221216,0.0009310331,0.00008195661,0.00002955843,0.0002874048],"genre_scores_gemma":[0.9934475,0.005395225,0.0005997411,0.00002391032,0.0002509583,0.00003112827,0.00003194896,0.00002752616,0.0001920636],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05945438,"threshold_uncertainty_score":0.4947888,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03852223527307915,"score_gpt":0.2670060912944626,"score_spread":0.2284838560213834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}