{"id":"W4250754662","doi":"10.1182/blood.v120.21.962.962","title":"Treatment of Severe Relapsing-Remitting Multiple Sclerosis with High-Dose Immunosuppressive Therapy and Autologous Hematopoietic Cell Transplantation: 2-Year Follow-up Results of the HALT MS Clinical Trial (Immune Tolerance Network: ITN033AI)","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"Polyomavirus and related diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; Multiple sclerosis; Transplantation; Internal medicine; Adverse effect; Prednisone; Surgery; Hematopoietic stem cell transplantation; Clinical endpoint; Busulfan; Clinical trial; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0047886,0.0009395012,0.002107307,0.0004199915,0.0006057661,0.001332306,0.0006423001,0.0015585,0.001641199],"category_scores_gemma":[0.001783925,0.0003306864,0.001732061,0.0004338169,0.0006083606,0.0008042522,0.0004086325,0.00235764,0.000431535],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005407221,"about_ca_system_score_gemma":0.0006784956,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009849698,"about_ca_topic_score_gemma":0.001106586,"domain_scores_codex":[0.9988887,0.0006561546,0.00006090798,0.00009849658,0.0001191285,0.000176664],"domain_scores_gemma":[0.9982332,0.0003484893,0.0004366357,0.0001822993,0.0001487688,0.0006506578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8567405,0.02064753,0.03870163,0.0005146034,0.003667179,0.0003482721,0.0002143266,0.001645105,0.006475492,0.0001969022,0.003800916,0.06704751],"study_design_scores_gemma":[0.438288,0.3958614,0.1544252,0.0001205075,0.00245683,0.0004150305,0.0001060779,0.001961362,0.00249377,0.000303308,0.00350531,0.00006321743],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916152,0.003633222,0.0003173364,0.0004332745,0.0001236443,0.0005618101,0.001269831,0.00004341086,0.002002205],"genre_scores_gemma":[0.9912294,0.001100097,0.0004108697,0.0008020367,0.0002449332,0.0006096396,0.003574796,0.00001353658,0.002014666],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0047886,"threshold_uncertainty_score":0.02532482,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03852223527307915,"score_gpt":0.2670060912944626,"score_spread":0.2284838560213834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}