{"id":"W4250951583","doi":"10.22215/etd/2015-11837","title":"Mass Spectrometry-Based Analysis to Investigate the Physiochemical and Proteomic Properties of Viral Sensitizers","year":2015,"lang":"en","type":"dissertation","venue":"","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"","keywords":"Oncolytic virus; Mass spectrometry; Chemistry; Computational biology; Liquid chromatography–mass spectrometry; Metabolomics; Chromatography; Biology; Virus; Virology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005621725,0.0006856041,0.0005202316,0.001648161,0.0004384828,0.000657356,0.0003404415,0.0006363565,0.002297853],"category_scores_gemma":[0.0006292876,0.0002656633,0.0005161529,0.0009258924,0.0003069832,0.000555807,0.00034498,0.0009606531,0.001147073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004165955,"about_ca_system_score_gemma":0.0005226481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006474429,"about_ca_topic_score_gemma":0.000957913,"domain_scores_codex":[0.9996614,0.00003117453,0.00001787473,0.00007634641,0.0001754274,0.00003775815],"domain_scores_gemma":[0.9997161,0.00006012106,0.00006465617,0.00002089157,0.0001072162,0.00003088793],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006398949,0.00004845433,0.0007045671,0.00009321423,0.00003194427,0.00004060265,0.00002364123,0.00009674922,0.990366,0.0001849127,0.0001539812,0.0081919],"study_design_scores_gemma":[0.00001459256,0.0002194694,0.00998854,0.00001486781,0.00005136347,0.0003268757,0.0000590141,0.00184137,0.9824272,0.0002212456,0.004818397,0.00001700269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.840165,0.02157738,0.1159167,0.0008796958,0.00032894,0.0007242294,0.006654839,0.001211516,0.01254167],"genre_scores_gemma":[0.862572,0.01580259,0.09629063,0.001208443,0.0001062147,0.0005361316,0.003947383,0.0002611788,0.01927546],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002297853,"threshold_uncertainty_score":0.007687092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0177399809309188,"score_gpt":0.2887447059397943,"score_spread":0.2710047250088755,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}