{"id":"W4251335479","doi":"10.1002/ange.202002019","title":"A Multi‐component All‐DNA Biosensing System Controlled by a DNAzyme","year":2020,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Deoxyribozyme; Biosensor; DNA; Chemistry; RNA; Nanotechnology; Substrate (aquarium); Biophysics; Combinatorial chemistry; Biochemistry; Biology; Materials science; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002977497,0.00062503,0.000457003,0.0003405443,0.000195145,0.0006951377,0.0009987639,0.0006336147,0.0009527444],"category_scores_gemma":[0.0002807265,0.0005112591,0.0002960951,0.0002166568,0.000314972,0.0006506906,0.0004961126,0.0006945821,0.0006767029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003235028,"about_ca_system_score_gemma":0.0002101993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002207042,"about_ca_topic_score_gemma":0.0002051831,"domain_scores_codex":[0.9996117,0.00004587728,0.00002523887,0.0001445724,0.0001393743,0.00003325081],"domain_scores_gemma":[0.9997872,0.00004578747,0.00006325592,0.00002551635,0.000037528,0.00004067632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003689616,0.00001455184,0.00006636118,0.00002767311,0.000005186529,0.00002765428,0.00001038292,0.0001535944,0.9966157,0.000209904,0.00004229113,0.002789673],"study_design_scores_gemma":[0.00001060533,0.0001186984,0.0001468741,0.000001836442,0.000008624237,0.00008167783,0.000003907926,0.002800733,0.99466,0.00004191175,0.002116951,0.000008280705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7368578,0.001920857,0.2543394,0.0003549179,0.0002710695,0.0002463209,0.0002337704,0.002422591,0.003353108],"genre_scores_gemma":[0.8144675,0.0005713264,0.17544,0.0001478068,0.00004644494,0.0001994204,0.0002244086,0.0001246409,0.008778611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009987639,"threshold_uncertainty_score":0.003187239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01751563961120868,"score_gpt":0.25636265439406,"score_spread":0.2388470147828513,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}