{"id":"W4252206570","doi":"10.1210/en.141.7.2410","title":"Dissection of Differentially Regulated (G+C)-Rich Promoters of the Human Parathyroid Hormone (PTH)/PTH-Related Peptide Receptor Gene","year":2000,"lang":"en","type":"article","venue":"Endocrinology","topic":"Bone health and treatments","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Royal Victoria Hospital; Royal Victoria Regional Health Centre","funders":"National Cancer Institute","keywords":"Promoter; Repressor; Biology; Transfection; Molecular biology; Transcription (linguistics); Housekeeping gene; Parathyroid hormone; Gene; CpG site; Response element; Transcription factor; Cell biology; Gene expression; Internal medicine; Genetics; DNA methylation; Medicine; Calcium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001067922,0.0002148908,0.0001300596,0.0001536252,0.0001035608,0.0002360836,0.0001681997,0.0001820521,0.0005055004],"category_scores_gemma":[0.000164034,0.0002021555,0.0002637719,0.0001057552,0.0001991066,0.00008546965,0.0001748643,0.000396537,0.0004093071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002760831,"about_ca_system_score_gemma":0.0003371813,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001251183,"about_ca_topic_score_gemma":0.00184046,"domain_scores_codex":[0.9999102,0.00001679216,0.000008298955,0.00002327299,0.00002271374,0.0000186065],"domain_scores_gemma":[0.9998914,0.00003915063,0.00002859806,0.00001040489,0.00000977621,0.00002066214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001258339,0.0000129457,0.0002208879,0.0000137405,0.000001545441,0.00003143647,0.00001163867,0.0001077784,0.998666,0.00006747851,0.00000890001,0.0007317961],"study_design_scores_gemma":[0.00003611502,0.0001818007,0.00902362,0.00001212549,0.00001560091,0.0002847803,0.00002682568,0.002941062,0.9858597,0.00009095945,0.0015193,0.000008164785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99369,0.0004836343,0.004733221,0.0000423338,0.000009915764,0.00004181658,0.0003607798,0.0000496766,0.0005885433],"genre_scores_gemma":[0.992109,0.0003051507,0.00618893,0.00004531548,0.00000528555,0.0000346262,0.0006195097,0.00003167627,0.0006603681],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001251183,"threshold_uncertainty_score":0.002487779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01316928389153351,"score_gpt":0.2667269555212298,"score_spread":0.2535576716296963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}