{"id":"W4252341638","doi":"10.1182/blood-2019-123483","title":"Four-Year Follow-up of the Phase 3 Pollux Study of Daratumumab Plus Lenalidomide and Dexamethasone (D-Rd) Versus Lenalidomide and Dexamethasone (Rd) Alone in Relapsed or Refractory Multiple Myeloma (RRMM)","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; Queen Elizabeth II Health Sciences Centre; Institute of Cancer Research; University of Calgary","funders":"","keywords":"Lenalidomide; Daratumumab; Medicine; Internal medicine; Dexamethasone; Multiple myeloma; Oncology; Surgery; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01053745,0.001087975,0.003517722,0.0007503697,0.001200528,0.002253364,0.001048984,0.002412363,0.004224603],"category_scores_gemma":[0.007774939,0.000761073,0.004645282,0.0008025813,0.0007703644,0.002452726,0.001313118,0.005367324,0.001279816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001352314,"about_ca_system_score_gemma":0.001266718,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002662516,"about_ca_topic_score_gemma":0.003553021,"domain_scores_codex":[0.9967835,0.001416025,0.0002468738,0.0005231075,0.0004842078,0.0005462591],"domain_scores_gemma":[0.9930176,0.001296473,0.001819468,0.0007722859,0.001010069,0.002084183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7206764,0.01243639,0.1248847,0.0008220657,0.02032558,0.0005501138,0.0006431604,0.002679006,0.005134644,0.000345328,0.01282477,0.09867789],"study_design_scores_gemma":[0.1198715,0.2400663,0.5981643,0.0002599968,0.02095539,0.0009975262,0.0005247497,0.002555104,0.002589553,0.0009303359,0.01285627,0.0002288908],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9704834,0.01192183,0.001140822,0.001509462,0.0006452883,0.00115278,0.007896665,0.0001587046,0.005090934],"genre_scores_gemma":[0.9822028,0.00143293,0.000550048,0.00223126,0.0002613004,0.0006541479,0.009110624,0.00004185127,0.00351494],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01053745,"threshold_uncertainty_score":0.05572802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05240809702567301,"score_gpt":0.3185706646804925,"score_spread":0.2661625676548195,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}