{"id":"W4252404860","doi":"10.1002/ange.201607483","title":"Isotopologous Organotellurium Probes Reveal Dynamic Hypoxia In Vivo with Cellular Resolution","year":2016,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Nanoplatforms for cancer theranostics","field":"Engineering","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"In vivo; Mass cytometry; Oxygenation; Hypoxia (environmental); Chemistry; Biophysics; Cell biology; Flow cytometry; Cancer cell; Biology; Phenotype; Molecular biology; Biochemistry; Oxygen; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001279399,0.0001974876,0.0001257794,0.0001489407,0.0001088451,0.0002541661,0.0002100214,0.0003441759,0.0009496966],"category_scores_gemma":[0.000156863,0.0001263746,0.00009564465,0.0000990722,0.0002520471,0.0002327805,0.0002293814,0.0003930031,0.0002147057],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002482784,"about_ca_system_score_gemma":0.0001155953,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003645065,"about_ca_topic_score_gemma":0.0005534893,"domain_scores_codex":[0.9999381,0.000006876698,0.000003342692,0.00001839282,0.00001912668,0.0000142376],"domain_scores_gemma":[0.999881,0.00004002925,0.00003796792,0.00001083916,0.0000154221,0.00001471402],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002193062,0.000002415872,0.00005430864,0.000008676927,0.000001024557,0.00001079455,0.000009225871,0.00007842095,0.9991129,0.00009687778,0.0000179271,0.0005854274],"study_design_scores_gemma":[0.000002262195,0.00003822763,0.0002925983,0.000001062177,0.000002147715,0.00003715109,0.00000907392,0.001036963,0.9980729,0.00003919756,0.0004667507,0.000001741661],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9736792,0.0007493135,0.02296241,0.00009068169,0.0000154468,0.00001832356,0.0001568312,0.0001213814,0.002206427],"genre_scores_gemma":[0.9828536,0.0004821542,0.0143647,0.0000535127,0.000007814844,0.00003027747,0.0001024359,0.00002458268,0.002080977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009496966,"threshold_uncertainty_score":0.003177106,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005834314021101339,"score_gpt":0.1869818233739951,"score_spread":0.1811475093528937,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}